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Platelet-driven immunothrombotic remodeling programs convert ectopic endometrium into fibrotic, immune-privileged lesions.

Endometriosis is a chronic, heterogenous disorder in which cyclical hemorrhage and repetitive repair generate ectopic implants that persist, recur, and drive pain and infertility; conventional frameworks emphasizing hormonal aberration and …

Published: July 18, 2026, midnight
Long-term insights: Seven years of conservative management for deep endometriosis in the bowel.

Deep endometriosis (DE) involving the bowel presents a complex management challenge. While surgery is often emphasized, limited evidence exists on long-term outcomes of conservative (non-surgical) management. This study aimed to …

Published: July 17, 2026, midnight
Tubal Pathology on Hysterosalpingography in Women with Unoperated Endometriomas: a Comparative Analysis.

This matched comparative study investigates whether unoperated ovarian endometriomas (OMAs) influence the prevalence of tubal pathology as detected by hysterosalpingography (HSG) in infertile women. A total of 266 infertile women …

Published: July 17, 2026, midnight
Patient-tailored symptom tracking in endometriosis: a framework to explore disease variability and burden.

Endometriosis is a chronic, estrogen-dependent inflammatory disease characterized by highly individualized, multisystemic symptoms, affecting approximately 10% of females. In this work, we present a long-term prospective study in which 34 …

Published: July 17, 2026, midnight
Right-Sided Mixed Intrinsic and Extrinsic Ureteral Endometriosis Leading to a Nonfunctioning Kidney: A Case Report.

Ureteral endometriosis is a rare form of urinary tract endometriosis that may cause silent ureteral obstruction and irreversible renal damage. Mixed intrinsic and extrinsic ureteral involvement is uncommon, and right-sided …

Published: July 17, 2026, midnight
Symptoms and distress across the menstrual cycle in a representative sample of Austrian and German people who menstruate: A cross-sectional study.

BackgroundPeople who menstruate may experience a range of symptoms, which, fluctuating throughout the different cycle phases, can interfere with their normal functioning. To date, research mostly investigated pain and psychological …

Published: July 16, 2026, midnight
Rheumatic Heart Disease: Inflammation, Immune Pathways, Valve Remodeling, and the Promise of SGLT2 Inhibitors.

Rheumatic heart disease (RHD) remains the leading cause of acquired valvular heart disease in low- and middle-income countries, affecting an estimated 40 million individuals and disproportionately affecting children and young …

Published: July 16, 2026, midnight
Adjunctive vitamin D supplementation in women receiving dienogest therapy for endometriosis: a randomized controlled trial.

Endometriosis is a chronic, estrogen-dependent inflammatory disease that causes debilitating pain and significantly impairs quality of life. Due to its anti-inflammatory and immunomodulatory properties, vitamin D has been proposed as …

Published: July 16, 2026, midnight
Mendelian randomization of risk factors for premenstrual disorders.

The causal role of established risk factors for premenstrual disorders (PMDs) remains unclear. We used Mendelian randomization (MR) to assess causality for eight known-risk factors identified through a literature review. …

Published: July 16, 2026, midnight
Endometriosis Unveiled: Innovations in Diagnosis and Management of Endometriosis.

Endometriosis is a chronic inflammatory condition that can result in chronic pain through complex nociceptive, neuropathic, and nociplastic pathways. This article provides a comprehensive background on endometriosis as well as …

Published: July 15, 2026, midnight
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