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The Reproductive Tract Microbiome and Female Fertility: Dysbiosis, Disease Links, and Emerging Therapeutic Strategies.

The reproductive tract microbiome plays a pivotal role in female fertility, with Lactobacillus-dominated communities maintaining a protective, low-pH environment. Dysbiosis-characterized by a reduction in Lactobacillus species and overgrowth of anaerobes-is …

Published: Jan. 21, 2026, midnight
Immunohistochemical Detection of the Mechano-Gated Piezo Channels in the Normal Endometrium and in Endometriosis.

Endometriosis is an inflammatory estrogen-dependent disorder characterized by pain, dyspareunia, dysmenorrhea, and infertility. This is due to the invasion of different organs by endometrial tissue that causes inflammation, angiogenesis, and …

Published: Jan. 19, 2026, midnight
Cholesterol granuloma forming the solid components within an endometrioma showing intense FDG uptake, mimicking malignancy: A case report.

A mural solid component (SC) within an endometrioma (ovarian endometriotic cyst), demonstrating internal vascularity or increased fluorodeoxyglucose (FDG) uptake on positron emission tomography (PET), is considered a characteristic finding suggestive …

Published: Jan. 19, 2026, midnight
Bidirectional causal relationship between 91 blood cells and endometriosis at different sites: A Mendelian randomization study.

To explore the genetic associations between 91 types of blood cells (BCs) and endometriosis (EMs), providing references for the treatment of EMs. Forward Mendelian randomization (MR) analysis was conducted with …

Published: Jan. 11, 2026, midnight
Anatomical distribution of ovarian and deep endometriosis using a multimodal diagnostic approach applying the updated international definition: A prospective observational study.

To (1) determine how application of the updated international definition of deep endometriosis (DE) alters apparent disease prevalence across pelvic sites, and (2) characterize the distribution of endometriosis phenotypes, including …

Published: Jan. 10, 2026, midnight
Intraoperative transvaginal ultrasound to refine surgical strategy in rectosigmoid endometriosis.

To explore the role of intraoperative transvaginal ultrasound in surgical planning for bowel deep endometriosis involving the rectum, rectosigmoid junction, and inferior sigmoid colon [1].

Published: Jan. 9, 2026, midnight
Navigating Complexity: Review and Updates of Endometriosis and Adenomyosis Imaging.

Endometriosis and adenomyosis are prevalent chronic inflammatory conditions that significantly impact reproductive-age women, leading to debilitating symptoms such as pelvic pain, dysmenorrhea, and infertility. Endometriosis is characterized by ectopic endometrial …

Published: Jan. 8, 2026, midnight
Microbiota and infertility: a translational review of mechanisms and clinical applications in assisted reproduction.

Infertility constitutes a major global health concern, affecting approximately 17.5% of couples of reproductive age. Although advances in assisted reproductive technologies (ART) have expanded treatment options, success rates remain highly …

Published: Jan. 5, 2026, midnight
Noninvasive BCL6 Preoperative Screening and Anatomic Patterns of Endometriosis in Patients with Unexplained Infertility.

Background/Objectives: Endometriosis is a chronic, inflammatory, estrogen-dependent disease that has historically been underdiagnosed, especially in patients with unexplained infertility. On average, diagnosis is delayed by 11 years, underscoring the need …

Published: Jan. 4, 2026, midnight
Vaginal Contraception With NuvaRing Decreases Symptoms and Uterine Features of Adenomyosis: A Prospective Evaluation.

(Abstracted from Contraception 2025:150:111016, doi:10.1016/j.contraception.2025.111016) Adenomyosis occurs when ectopic endometrial glands invade the myometrium and can cause symptoms such as an enlarged uterus, heavy menstrual bleeding, pelvic pain, infertility, and …

Published: Dec. 31, 2025, midnight
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