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Human versus machine: Assessing the Allplex™ bacterial vaginosis plus assay (Seegene®) using Ison-Hay criteria and cut-off values interpretations in pregnant population.

Bacterial vaginosis (BV) is a common dysbiotic condition associated with adverse pregnancy outcomes, including preterm delivery, and its diagnosis remains challenging due to limitations of conventional methods and the lack …

Published: July 28, 2026, midnight
Elucidating behavioral and environmental barriers to clinicians' engagement in endometriosis diagnostic practices: a mixed-methods scoping review.

Endometriosis is an estrogen-dependent chronic systemic inflammatory disease that affects 10 % of people assigned female at birth. Despite its prevalence, mean diagnostic delay is 4-11 years. Although much research …

Published: July 27, 2026, midnight
Fertile Ground for Collaboration: A survey of pediatric surgeons on pediatric and adolescent gynecologic care.

Pediatric and Adolescent Gynecology (PAG) emerged to bridge gaps between pediatrics and adult gynecology, while pediatric surgeons currently provide most operative gynecologic care for young patients. The goal of this …

Published: July 26, 2026, midnight
Endometriosis-Associated Implantation Failure: Pathophysiology, Biomarkers, and Emerging Therapeutic Strategies.

Implantation failure remains a major challenge in assisted reproductive technology (ART) and is a significant contributor to infertility in women with endometriosis. Beyond mechanical distortion and ovarian dysfunction, increasing evidence …

Published: July 24, 2026, midnight
Hierarchical attention and frequency fusion network for endometriotic lesion detection in laparoscopic images.

Endometriosis is a common gynecological disorder that requires accurate detection of ectopic lesions in laparoscopic images for effective diagnosis and treatment. However, existing deep learning-based detection methods face significant challenges …

Published: July 23, 2026, midnight
The Molecular and Cellular Mechanisms of Melatonin: From Physiological Actions to Clinical Applications in Reproductive Medicine.

Melatonin has evolved from its classical role as a pineal-derived circadian regulator to a molecule increasingly recognized for its mitochondrial and cytoprotective functions. This review examines the molecular mechanisms and …

Published: July 22, 2026, midnight
Integrating single-cell and bulk transcriptomic perturbation resources reveals complementary therapeutic spaces for drug repurposing.

Transcriptome-based drug repurposing can accelerate therapeutic discovery, but is limited by fragmented resources, inconsistent quality control, and reliance on single perturbation databases. We developed CDRPipe ( C omputational D rug …

Published: July 22, 2026, midnight
p53-mediated epigenetic regulation in the pathogenesis of endometriosis.

Endometriosis (EMs) is a common gynecological disorder affecting reproductive‑aged women, characterized by ectopic endometrial growth and chronic pelvic pain that severely impairs quality of life. Although its pathogenesis remains incompletely …

Published: July 21, 2026, midnight
Robotic-assisted compared to conventional laparoscopic surgery for colorectal endometriosis: perioperative outcomes in the context of #Enzian-defined anatomical complexity.

The objective of this work was to compare the perioperative safety and operative efficacy of robotic-assisted surgery (RAS) versus conventional laparoscopy surgery (CLS) in women with symptomatic colorectal endometriosis, with …

Published: July 20, 2026, midnight
Reply to "Reassessing the Proposed Creatine-PrP Axis in Endometriosis: Methodological and Mechanistic Considerations".

This Correspondence is a formal response to the Comment by Dr. Machado regarding our publication "Creatine Promotes Endometriosis by Inducing Ferroptosis Resistance via Suppression of PrP." We address several conceptual …

Published: July 20, 2026, midnight
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