Latest Articles

Noninvasive BCL6 Preoperative Screening and Anatomic Patterns of Endometriosis in Patients with Unexplained Infertility.

Background/Objectives: Endometriosis is a chronic, inflammatory, estrogen-dependent disease that has historically been underdiagnosed, especially in patients with unexplained infertility. On average, diagnosis is delayed by 11 years, underscoring the need …

Endometriosis and Reproductive Sparing Surgery: A Narrative Review and AGREE II-S-Based Evaluation of International Guidelines.

Endometriosis is a complex disease that may affect a woman's fertility and quality of life. Owing to substantial variations in symptom severity, lesion distribution, and reproductive impact, its management presents …

Expanded Histologic Lineage and Origin of Mesonephric-Like Adenocarcinoma: A Clinicopathologic Study of 9 Cases.

Mesonephric-like adenocarcinoma (MLA) is a rare gynecologic malignancy primarily arising in the uterine corpus and ovaries. It shares remarkable similarities in its histomorphology, immunophenotype, and molecular features with mesonephric adenocarcinoma …

Clinical diagnosis and treatment of bowel endometriosis and the distribution characteristics of lesions.

Pharmacokinetic-Pharmacodynamic Modeling and Simulation of Merigolix, a Nonpeptide Gonadotropin-Releasing Hormone Antagonist.

Gonadotropin-releasing hormone (GnRH) antagonists inhibit estrogen synthesis and secretion, making them promising treatment options for estrogen-dependent diseases, such as endometriosis. This study developed a population pharmacokinetic/pharmacodynamic (PK/PD) model for merigolix, …

Histomorphometric characterization of the endometrium in mules (Equus mulus): An approach to endometritis/endometrosis.

Mules (Equus mulus), as sterile hybrids between mares and donkeys, present a unique uterine morphology and physiology that remains poorly characterized. This study provides the first histomorphometric evaluation and transcriptional …

A Unique Case Series of Endometrial Vascular Dystrophy: Rising Incidence and Association With Uterine Pathologies.

Endometrial vascular dystrophy (EVD) is a rare hysteroscopic finding characterized by abnormal, tortuous, and dilated endometrial vessels, most often associated with abnormal uterine bleeding (AUB). Despite its potential clinical impact, …

TCGA molecular subtypes in endometriosis-associated ovarian cancer: a systematic review and meta-analysis.

Endometriosis-associated ovarian cancer (EAOC) mainly includes endometrioid ovarian cancer (ENOC) and clear cell ovarian cancer (CCOC). The Cancer Genome Atlas (TCGA) revealed four molecular subtypes of endometrial cancer (EC) in …

Inpatient Endometriosis Care in Germany: Hospital Caseloads and their Spatial Distribution.

Endometriosis is a chronic gynaecological disease with an estimated prevalence of 10-15%. The German guideline provides evidence-based recommendations for diagnosis and treatment, but care provided is inadequate care due to …

Lateral distribution of endometriotic lesions: the anatomical recesses hypothesis. A systematic review and meta-analysis.

Are endometriotic lesions affecting bilateral organs or anatomical structures distributed symmetrically on both sides of the body?