Research progress of ferroptosis in gynecological diseases.
The concept of ferroptosis debuted as a newly defined programmed cell death in 2012. Among programmed cell death mechanisms, ferroptosis stands out as being fundamentally dependent on iron. At the …
Primary umbilical endometriosis masquerading as strangulated umbilical hernia: a diagnostic pitfall.
Primary umbilical endometriosis (Villar's nodule) is a rare entity, representing 0.5%-1% of all endometriosis cases. We report a 37-year-old multiparous woman presenting with a 7-day history of umbilical pain, swelling, …
RNF34 restrains endometriosis through SREBP1-dependent metabolic-immune crosstalk.
Endometriosis is a chronic inflammatory disease with cancer-like features, yet the mechanisms linking metabolic dysregulation to immune remodeling during lesion progression remain poorly understood. Here, we identify the ubiquitin E3 …