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Single-Cell Profiling Reveals Altered Endometrial Cellular Features Across the Menstrual Cycle in Endometriosis Patients.

Endometriosis is a chronic, estrogen-dependent condition affecting over 190 million women globally, characterized by the ectopic presence of endometrial-like tissue that leads to inflammation, pain, and infertility. Despite its prevalence, …

Published: Aug. 14, 2025, midnight
Global, regional, and national burdens of endometriosis from 1990 to 2021: a trend analysis.

Endometriosis is a common, chronic, estrogen-dependent gynecological disorder that significantly affects patients' quality of life. However, the disease burden and its trends may be undergoing significant changes, and comprehensive data …

Published: Aug. 14, 2025, midnight
The role of TGF-β superfamily in endometriosis: a systematic review.

Endometriosis is a prevalent chronic gynecological disorder. Globally, endometriosis affects approximately 5-10% of women of reproductive age, leading to symptoms such as dysmenorrhea, chronic pelvic pain, and infertility. While the …

Published: Aug. 12, 2025, midnight
C57BL/6J mice best recapitulate fibrosis and inflammatory pathophysiology in syngeneic mouse model of endometriosis.

Endometriosis (ENDO), a chronic inflammatory disease affecting approximately 190 million women globally, is characterized by fibrosis, a feature often challenging to replicate in murine models. To identify an optimal syngeneic …

Published: Aug. 8, 2025, midnight
Breaking Down Barriers: Improving Access to Quality Endometriosis Care.

Endometriosis affects an estimated 200 million women globally, yet significant barriers hinder access to timely and appropriate care. These barriers encompass various aspects, including societal normalization of menstrual pain, leading …

Published: Aug. 7, 2025, midnight
Unraveling the Core of Endometriosis: The Impact of Endocrine Disruptors.

Globally, endometriosis affects almost 10% of reproductive-aged women, leading to chronic pain and discomfort. Endocrine-disrupting compounds (EDCs) seem to play a pivotal role as a causal factor. The current manuscript …

Published: Aug. 6, 2025, midnight
Factors affecting healthcare access for dysmenorrhoea: a scoping review protocol.

Dysmenorrhoea (period pain) is a global public health issue affecting up to 91% of the 1.8 billion individuals who menstruate. While research has emphasised the improvement of menstrual health in …

Published: Aug. 6, 2025, midnight
Global, regional, and national prevalence and trends of gynecological diseases among women of childbearing age from 1990 to 2021: An analysis of the global burden of disease study 2021.

The global prevalence and trends of gynecological diseases (GDs) among women of childbearing age (WCBA) remain unclear and may be underestimated. This study aims to evaluate the prevalence of GDs …

Published: Aug. 1, 2025, midnight
Factors contributing to the delayed diagnosis of endometriosis-a systematic review and meta-analysis.

Endometriosis is a prevalent gynecological disorder that is estimated to affect approximately 10% of women of childbearing age globally. However, the condition remains significantly under-or misrecognized, and the mean time …

Published: July 22, 2025, midnight
Non-Hormonal Strategies in Endometriosis: Targets with Future Clinical Potential.

Endometriosis is a chronic gynecological pathology marked by the aberrant proliferation of tissue analogous to the endometrial lining outside the uterine cavity. This disorder frequently engenders persistent pelvic discomfort, infertility, …

Published: July 17, 2025, midnight
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