Latest Articles

AI-Enhanced MRI Radiomics for Discriminating Active and Fibrotic Lesions to Support Therapeutic Decision-Making in Deep Endometriosis.

This study investigates whether quantitative analysis of preoperative Magnetic Resonance Imaging (MRI) scans can differentiate deep infiltrating endometriosis (DIE) lesion types (active or fibrotic) and associate them with reported pain …

SLC25A1-Mediated Cholesterol Accumulation Promotes Endometriosis Progression by Enhancing Endometrial Stromal Cell Proliferation, Invasion, and M2 Macrophage Polarization.

Endometriosis is an estrogen-dependent chronic inflammatory disorder. Cholesterol (CHO) has been reported to be closely associated with estrogen synthesis and inflammatory responses. Nevertheless, the mechanisms underlying the effects of cholesterol …

Rectosigmoid Endometrioma Mimicking Rectal Hematoma: A Diagnostic Dilemma Managed Conservatively.

Endometriosis is a benign gynecological condition characterized by the presence of functional endometrial tissue outside the uterine cavity. Although it most commonly affects pelvic organs, bowel involvement is uncommon, and …

Clinical diagnosis and treatment of bowel endometriosis and the distribution characteristics of lesions.

Malignant Transformation Associated with Endometrioid Adenocarcinoma of Abdominal Wall Endometriosis: A Case Report and Literature Review.

Endometriosis is a prevalent chronic gynecological disease, characterized by the growth of endometrial glands and stroma outside the uterus and by the presence of chronic inflammatory lesions. This condition is …

Vascular graph network for ovarian lesion classification using optical-resolution photoacoustic microscopy.

Diagnosing ovarian lesions is challenging because of their heterogeneous clinical presentations. Some benign ovarian conditions, such as endometriosis, can have features that mimic cancer. We use optical-resolution photoacoustic microscopy (OR-PAM) …

Human Endometriosis Scaffold Can Enhance Cell Seeding and Engraftment; an In Vitro and In Vivo Study.

The extracellular matrix (ECM) critically influences cell behavior, yet its properties in human endometrial lesions (HEL) and human uterine fibromas (HUF) are not well characterized. This study aimed to characterize …

Longitudinal ultrasound-based follow up of non-surgically treated endometriosis using #Enzian classification.

This study aimed to compare clinical and ultrasound outcomes over 24 months in premenopausal women with ultrasound-diagnosed endometriosis/adenomyosis, never treated surgically, and managed with or without hormonal therapy. We specifically …

Molecular Imaging Advances in Endometriosis: The Promise of Radiopharmaceuticals.

Endometriosis is a highly prevalent, chronic gynecological disorder characterized by the ectopic presence of endometrial-like tissue, driving significant morbidity and chronic pelvic pain. Pathologically, it is increasingly recognized as a …

Targeting inflammation in endometriosis: emerging therapeutic options.

Endometriosis is a chronic, estrogen-dependent inflammatory disease affecting up to 10% of reproductive-aged women. Current therapies are predominantly hormone-based and offer symptomatic relief without correcting the immune dysregulation and inflammation …