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Single-cell and spatially resolved omics reveal transcriptional and metabolic signatures of ovarian endometriomas.

Endometriosis involves ectopic growth of endometrial-like tissue, yet the spatial transcriptomic and metabolic landscape of ovarian endometriomas remains poorly understood. This investigation presents a comprehensive multi-omics analysis of ovarian endometriomas …

Published: Nov. 22, 2025, midnight
Metabolome analysis as a potential source of endometriosis biomarkers with the use of multiomics approach in its diagnosis.

Endometriosis poses diagnostic challenges. This study aimed to analyze the metabolomic profiles of plasma and peritoneal fluid samples obtained from women with endometriosis compared to controls. Our multicenter study involved …

Published: Nov. 5, 2025, midnight
Integrative microbiome-metabolomics identifies Pseudomonas as a potential pathogenic factor in endometriosis.

Endometriosis (EMS) is a chronic disease characterized by unclear etiology, influenced by various genetic and environmental factors, with no definitive biomarkers available for early screening. Recent studies suggest that the …

Published: Oct. 30, 2025, midnight
Follicular Fluid Amino Acid Alterations in Endometriosis: Evidence for Oxidative Stress and Metabolic Dysregulation.

Background/Objectives: Endometriosis (EM) is a chronic gynecological condition associated with infertility, oxidative stress, and altered metabolic regulation. Follicular fluid (FF) reflects the microenvironment of the developing oocyte, and changes in …

Published: Oct. 27, 2025, midnight
Adiposity, Metabolites Linked to Endometrial Cancer - bioengineer.org

Adiposity, Metabolites Linked to Endometrial Cancer bioengineer.org

Published: Oct. 21, 2025, 2:27 p.m.
Adiposity, Metabolites Linked to Endometrial Cancer - Bioengineer.org

Adiposity, Metabolites Linked to Endometrial Cancer Bioengineer.org

Published: Oct. 21, 2025, 2:27 p.m.
Adiposity, Metabolites Linked to Endometrial Cancer - BIOENGINEER.ORG

Adiposity, Metabolites Linked to Endometrial Cancer BIOENGINEER.ORG

Published: Oct. 21, 2025, 2:27 p.m.
Serum Fingerprinting-Based Integrative Dual-Omics Machine Learning for Endometriosis-Associated Ovarian Cancer.

Dual-omics, by integrating molecular information from two distinct dimensions, can offer more comprehensive perspective for complex disease. Herein, we developed an efficient functionalized mesoporous nanoparticle-coupled laser desorption/ionization mass spectrometry (fMNPLDI-MS) …

Published: Oct. 16, 2025, midnight
The effect of phytoestrogens and PAHs on endometriosis and the involvement of gut microbiota, inflammation, and molecular targets.

Endometriosis is a common estrogen-dependent inflammatory disease, yet its complex etiology is not fully understood. Endocrine Disrupting Chemicals (EDCs) exposure disrupts human reproduction, but studies on mixed EDCs and endometriosis …

Published: Oct. 15, 2025, midnight
Identification and validation of lactate-related gene signatures in endometriosis for clinical evaluation and immune characterization by WGCNA and machine learning.

Endometriosis is a common benign gynecologic disease in women of reproductive age, and its manifestations remarkably decrease quality of life. Lactate, as a metabolite, exerts prominent effects across a wide …

Published: Oct. 7, 2025, midnight
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