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Lack of Scientific Evidence for the Use of Gestrinone in the Treatment of Lipedema: A Systematic Review.

Lipedema is a chronic, progressive disorder marked by the abnormal accumulation of subcutaneous adipose tissue, predominantly in the lower body and almost exclusively affecting women. In recent years, the off-label …

Published: Nov. 19, 2025, midnight
Gene regulation by non-Coding RNAs in infertility: a mechanistic review.

Infertility is a significant global health issue affecting millions of couples, with noncoding RNAs (ncRNAs) emerging as pivotal regulators in reproductive biology. This review explores the roles of various ncRNAs, …

Published: Nov. 17, 2025, midnight
Interventions for endometriosis-related pain and infertility: a protocol for systematic review and network meta-analysis.

Endometriosis, a chronic oestrogen-dependent disorder, presents significant clinical challenges including pelvic pain, dysmenorrhoea, dyspareunia and infertility. While numerous interventions exist, evidence guiding the choice among surgical, hormonal and non-hormonal therapies …

Published: Nov. 13, 2025, midnight
Improving Diagnostic Yield in Peritoneal Endometriosis: Value of Additional Level Sections and Sampling Protocols.

To evaluate whether deeper histologic sections and tissue-blocking practices improve the diagnosis of endometriosis in peritoneal biopsies. We retrospectively reviewed 148 peritoneal biopsy cases with clinical suspicion of endometriosis from …

Published: Oct. 23, 2025, midnight
Non-contrast MRI diagnostic protocol for pelvic venous disorders.

Pelvic venous disorders (PeVD) remain a challenging diagnosis due to their nonspecific clinical presentation and the limitations of current imaging techniques. Conventional imaging of this pathology frequently relies on ultrasound …

Published: Oct. 19, 2025, midnight
Addressing Meta-Inflammation in the Comprehensive Management of Chronic Pain.

Chronic pain is a widespread condition affecting millions globally, placing significant strain on healthcare systems, as evidenced by the current opioid crisis. Despite advances in pain management, conventional treatments often …

Published: Oct. 18, 2025, midnight
Pregnancy and obstetric-neonatal outcomes of patients with thin endometrium using three different endometrial preparation protocols in frozen embryo transfer cycles: a historical cohort of 2671 patients - BioMed Central

Pregnancy and obstetric-neonatal outcomes of patients with thin endometrium using three different endometrial preparation protocols in frozen embryo transfer cycles: a historical cohort of 2671 patients BioMed Central

Published: Oct. 15, 2025, 9:49 a.m.
Damage Control Surgery in Obstetrics and Gynecology: Abdomino-Pelvic Packing in Multimodal Hemorrhage Management.

Damage control surgery (DCS) is a staged surgical strategy for rapid control of life-threatening bleeding, followed by physiological stabilization and delayed definitive repair. Abdomino-pelvic packing (APP)-placing compressive material within the …

Published: Oct. 13, 2025, midnight
Symptom tracking for endometriosis: a systematic review protocol for mobile applications focused on content, inclusivity and features.

Endometriosis is a chronic gynaecological condition affecting 2%-10% of women worldwide, often leading to severe pain, organ dysfunction and infertility. Despite its prevalence, diagnosis is frequently delayed, and treatment options …

Published: Oct. 10, 2025, midnight
Nationwide evaluation of hepatitis medication prescription patterns and costs in hepatitis B and C care.

The financial and healthcare burden of hepatitis B and C remains a significant challenge in Iran, despite efforts to control these diseases through vaccination and improved treatment protocols. This study …

Published: Oct. 10, 2025, midnight
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