Evidence-based recommendations for advancing the chronic pelvic pain syndrome management by the paradigm change from reactive symptom suppression to proactive 3PM-guided patient-centered care.
Chronic pelvic pain syndrome (CPPS) encompasses a heterogeneous group of debilitating conditions including interstitial cystitis/bladder pain syndrome (IC/BPS), chronic abacterial prostatitis, endometriosis, and pelvic congestion syndrome, among others. Despite advances …
Platinum sensitivity drives prognosis in endometriosis-associated ovarian carcinoma compared with high-grade serous ovarian carcinoma: Insights from a 10-year retrospective study.
To compare clinical features, treatment responses, and survival outcomes between endometriosis-associated ovarian cancer (EAOC) and high-grade serous ovarian carcinoma (HGSOC), with a focus on platinum resistance.
L-ICON3 Suppresses Endometriosis in a Murine Model.
Endometriosis is a chronic, systemic gynecological disorder that affects 190 million women worldwide. Current treatments consist of hormonal suppression and surgical excision; however, both have considerable side effects and a …
From polygenic risk to functional genomics: a framework for precision gynecological disease modeling.
Gynecological conditions including endometriosis, polyendocrine metabolic ovarian syndrome and malignancies cause widespread chronic morbidity and infertility, yet translating genetic discoveries into biological mechanisms remains challenging. We propose a framework integrating …
Lack of socio-demographic participant diversity in endometriosis evidence risks unrepresentative clinical guidance: a structured review of a NICE guideline.