In Situ Characterization and Deep Profiling of Engineered Multispecific Nanoparticle Metabolite Coronas for Precise Serum Diagnostics.
Upon exposure to biofluids, engineered nanoparticles (NPs) spontaneously form reproducible biomolecular coronas via selective diverse biomolecule adsorption. The corona characterization of metabolites poses greater analytical challenges than proteins due to …
AI-Driven Advances in Women's Health Diagnostics: Current Applications and Future Directions.
Background: Women's health has historically served as an incubator for major medical innovations yet often faces relative neglect in sustained funding and implementation. The rise of artificial intelligence (AI) and …
Proteome-wide Mendelian randomization identifies β-nerve growth factor as a target for endometriosis.
Endometriosis is a chronic inflammatory disorder with poorly understood mechanisms. Inflammatory proteins are hypothesized to play a causal role, but evidence remains limited. We performed a 2-sample Mendelian randomization study …
Integrative microbiome-metabolomics identifies Pseudomonas as a potential pathogenic factor in endometriosis.
Endometriosis (EMS) is a chronic disease characterized by unclear etiology, influenced by various genetic and environmental factors, with no definitive biomarkers available for early screening. Recent studies suggest that the …