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Endometrial dysfunction in embryo implantation: from molecular mechanisms to clinical management.

Endometrial dysfunction represents a central pathological factor underlying recurrent implantation failure and infertility. This review provides a comprehensive synthesis of the physiological basis of endometrial function, the pathological factors compromising …

Published: June 18, 2026, midnight
Complex benign gynecology in perimenopause: current evidence and future directions.

Perimenopause is a clinically distinct stage in which abnormal uterine bleeding, fibroids, adenomyosis, endometriosis, and adnexal pathology may require surgical evaluation. Management is complex because symptom burden and structural disease …

Published: June 17, 2026, midnight
Malignant transformation of uterine serosal endometriosis to clear cell carcinoma in a postmenopausal patient: a rare case report.

Endometriosis is a prevalent benign condition among women of reproductive age. While the overall rate of endometriosis-associated malignancy is low, the risk of malignant transformation increases significantly in postmenopausal patients, …

Published: June 17, 2026, midnight
A logistic regression model for predicting postoperative recurrence of cellular uterine leiomyoma.

The risk factors for the postoperative recurrence of cellular uterine leiomyoma (CUL) remain unclear.This study aimed to identify independent risk factors for recurrence and to develop a predictive model based …

Published: June 17, 2026, midnight
Uterine microbiome signatures associated with endometriosis.

Endometriosis is a chronic inflammatory disorder affecting ~ 10% of reproductive-age women, often causing pelvic pain and infertility. Despite its prevalence, diagnosis remains delayed due to non-specific symptoms and lack …

Published: June 16, 2026, midnight
The Scholarly Infrastructure of Complex Benign Gynecology: A Bibliometric Analysis of Publication Patterns, Citation Impact, and Field Maturation from 2015-2025.

To evaluate publication patterns of Complex Benign Gynecology (CBG) scholarship in specialized and general Obstetrics and Gynecology (OB/GYN) journals and assess their association with indicators of subspecialty maturation within the …

Published: June 15, 2026, midnight
Ceramide: a pivotal lipid mediator shaping female reproductive homeostasis and pathophysiology.

Ceramide, a central hub in sphingolipid metabolism, serves as a critical bioactive signalling mediator that integrates lipid metabolism with multiple signalling pathways, primarily promoting autophagy and apoptosis. It influences female …

Published: June 15, 2026, midnight
Burden and Trends of Six Gynecological Diseases Among Chinese Women Aged 15-49 Years, 1990-2021: Evidence from GBD 2021.

This study examines the burden of six gynecological system diseases (uterine fibroids, polycystic ovarian syndrome, endometriosis, cervical cancer, ovarian cancer, and uterine cancer) in Chinese women aged 15-49 years from …

Published: June 15, 2026, midnight
Mesenchymal Stem Cells Therapy for Intrauterine Adhesions and Endometriosis: Potential, Mechanisms, and Future Directions.

Intrauterine adhesions (IUA) and endometriosis are debilitating gynecological disorders that impair endometrial function and fertility. IUA, typically caused by iatrogenic trauma to the basal endometrium, leads to fibrosis and infertility, …

Published: June 14, 2026, midnight
The role of IL-33/ST2 signaling in female reproductive diseases.

Female reproductive tissues repeatedly undergo controlled inflammation, immune adaptation, and tissue repair. Interleukin-33 (IL-33) and its receptor suppression of tumorigenicity 2 (ST2) sit at the center of these processes, but …

Published: June 12, 2026, midnight
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