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Dyspareunia is rarely assessed in rodent models of endometriosis and interstitial cystitis/bladder pain syndrome: a systematic review.

Dyspareunia, or pain during sex, is a common and often-debilitating symptom in individuals with endometriosis and/or interstitial cystitis/bladder pain syndrome (IC/BPS). Despite its significant impact on quality of life, it …

Published: Dec. 1, 2024, midnight
The Evil Twins of Chronic Pelvic Pain Syndrome: A Systematic Review and Meta-Analysis on Interstitial Cystitis/Painful Bladder Syndrome and Endometriosis.

Chronic pelvic pain is a debilitating condition affecting quality of life. Endometriosis is one of the leading causes of CPP, but recent studies highlighted the role of interstitial cystitis/bladder pain …

Published: Nov. 29, 2024, midnight
miR-450b-5p promotes development of endometriosis by inhibiting the GABPA/HOXD10 axis.

Despite decades of research, the pathogenesis of endometriosis remains unclear. Recent studies have shown that microRNAs play an important role in this condition. In this study, we found that the …

Published: Nov. 28, 2024, midnight
Prevalence of thyroid autoantibody positivity in women with infertility: a systematic review and meta-analysis.

Thyroid autoimmunity (TAI) is associated with infertility and complications during pregnancy. However, the prevalence of thyroid autoantibodies in women with infertility remains unclear due to variability in study designs, sample …

Published: Nov. 27, 2024, midnight
Identification and verification of diagnostic biomarkers for deep infiltrating endometriosis based on machine learning algorithms.

This study addresses the challenges in the early diagnosis of deep infiltrating endometriosis (DIE) by exploring the potential role of the deubiquitinating enzyme USP14. By analyzing the GSE141549 dataset from …

Published: Nov. 25, 2024, midnight
Recent advances in understanding the role of uterine microbiota in endometrial receptivity and its impact on embryo implantation failure.

The aim was to provide a review of studies on the impact of intrauterine bacterial flora on endometrial tolerance in populations with failed embryo implantation and to provide direction for …

Published: Nov. 24, 2024, midnight
[Psychoemotional state and sexual function in women with chronic pelvic pain in genital endometriosis].

The purpose of this review is to consider current ideas about psychophysiology of chronic pelvic pain (CPP) in external genital endometriosis (GE), as well as the impact of the psychoemotional …

Published: Nov. 23, 2024, midnight
mTOR inhibitors as potential therapeutics for endometriosis: A narrative review.

Mammalian target of rapamycin (mTOR) inhibitors have been used clinically as anticancer and immunosuppressive agents for over 20 years, demonstrating their safety after long-term administration. These inhibitors exhibit various effects, …

Published: Nov. 23, 2024, midnight
Extracellular vesicle-packaged PKM2 from endometriotic stromal cells promotes endometrial collagen I deposition by inhibiting autophagy in endometriosis.

Aberrant endometrial collagen I deposition during the implantation window impairs endometrial stromal cell (ESC) decidualization, which may contribute to lower pregnancy rate in endometriosis (EMs) patients with in vitro fertilization …

Published: Nov. 23, 2024, midnight
Quality Improvement Report: The Sliding Sign Initiative-Facilitating Earlier Detection of Deep Endometriosis in an Academic US Department.

A delayed diagnosis of endometriosis can significantly impact a patient's quality of life. To facilitate an earlier diagnosis, we implemented a modified pelvic US protocol that included use of the …

Published: Nov. 22, 2024, midnight
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