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Probiotic supplementation improves quality of life and modulates oestradiol in women with endometriosis: a randomised double-blind pilot trial.

Endometriosis is a chronic, oestrogen-dependent inflammatory disorder affecting up to 10% of reproductive-age women, associated with pelvic pain, infertility, and reduced quality of life. Emerging evidence implicates the vaginal microbiome …

Published: March 27, 2026, midnight
Integrating Metabolic and MicroRNA Profiling to the Diagnostics of Endometriosis: A Pilot Study.

Endometriosis affects a large number of women of reproductive age, and its pathogenesis is still unclear. It causes severe chronic pelvic pain, which is often misdiagnosed as irritable bowel syndrome, …

Published: March 27, 2026, midnight
Contraceptive-Induced Weight Gain-Myth and Reality Review.

The perception that hormonal contraception causes weight gain is a general belief that frequently hinders the initiation and continuation of effective family planning. This narrative review analyses data from Cochrane …

Published: March 27, 2026, midnight
YWHAZ Loss Is Associated With Endometrial Dysfunction in Proliferative Phase Endometriosis.

Endometriosis is an estrogen-dependent inflammatory disorder frequently associated with infertility and characterized by progesterone resistance and impaired endometrial receptivity. While ectopic lesions define the disease, accumulating evidence indicates that molecular …

Published: March 26, 2026, midnight
Genetics of Endometriosis-Associated Ovarian Cancer: A Systematic Review.

Up to 1.6% of patients with endometriosis develop epithelial ovarian carcinoma. The genetic overlap between endometriosis and ovarian cancer has not been fully characterized. This review aims to describe the …

Published: March 26, 2026, midnight
Italian Expert Consensus on Women's Nutrition Across the Life Course: A Modified Delphi Study.

Objective: Nutrition is a key determinant of women's health across all life stages. Clinical practice remains heterogeneous because of lack of evidence and non-homogeneous guidelines. Despite growing research on micronutrient …

Published: March 26, 2026, midnight
Reduced GEN1 Expression Is Associated with Elevated DNA Damage and Impaired Proliferation in Endometriosis-Derived Endometrial Organoids.

Endometriosis affects approximately 10% of reproductive-age women and is associated with genomic instability; however, the contribution of specific DNA repair deficiencies remains poorly understood. This study investigated the expression and …

Published: March 26, 2026, midnight
A meta-umbrella review of risk factors for vulvodynia: evidence from demographic, psychosocial, and biomedical domains.

Vulvodynia is a chronic vulvar pain condition significantly affecting the quality of life. Its multifactorial etiology is not fully understood, and comprehensive pooled data on associated risk factors are lacking …

Published: March 25, 2026, midnight
MYC: unveiling novel therapeutic avenues for endometriosis.

Published: March 25, 2026, midnight
Endometrial epithelial cells with high ALDH activity control uterine development and regeneration.

Adult stem cells are thought to drive the regenerative potential of the endometrium and contribute to the pathogenesis of endometriosis, however, their identity and defining features remain to be characterized. …

Published: March 24, 2026, midnight
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