Latest Articles

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Immunohistochemical Evaluation of Potential Biomarkers for Targeted Intraoperative Fluorescence Imaging in Endometriosis: Towards Optimizing Surgical Treatment.

Surgical intervention for endometriosis is an important treatment modality, yet incomplete resection resulting from poor visibility of affected tissue and consequently recurrence of disease remains a prevalent challenge. Intra-operative visualization …

Published: Oct. 7, 2024, midnight
Influence of Mediterranean Diet on Sexual Function in People with Metabolic Syndrome: A Narrative Review.

Metabolic syndrome (MS), a cluster of cardiometabolic disorders, and sexual dysfunction are two conditions that impact a large proportion of the general population. Although they can occur independently, they are …

Published: Oct. 6, 2024, midnight
Endometriotic lesions and their recurrence: A Study on the mediators of immunoregulatory (TGF-β/miR-20a) and stemness (NANOG/miR-145).

Endometriosis is a common estrogen-dependent disease that involves various cellular processes. Additionally, miRNAs play a crucial role in the development of the disease as an important component of the microenvironment. …

Published: Oct. 1, 2024, midnight
Reply: Missing the target.

Published: Sept. 28, 2024, midnight
Exploring the Role of MicroRNAs in Progesterone and Estrogen Receptor Expression in Endometriosis.

Background/Objectives: Patients with endometriosis still respond poorly to progestins due to progesterone resistance associated with microRNAs (miRNAs). The aim of this study was to investigate the expression of selected miRNAs, …

Published: Sept. 28, 2024, midnight
PAK5-mediated PKM2 phosphorylation is critical for anaerobic glycolysis in endometriosis.

P21-activated kinase 5 (PAK5) belongs to the PAK-II subfamily, which is an important regulator of cell survival, adhesion, and motility. However, the functions of PAK5 in endometriosis remain unclear. Here, …

Published: Sept. 27, 2024, midnight
Targeting delivery of mifepristone to endometrial dysfunctional macrophages for endometriosis therapy.

Endometriosis seriously affects 6-10 % of reproductive women globally and poses significant clinical challenges. The process of ectopic endometrial cell colonization shares similarities with cancer, and a dysfunctional immune microenvironment, …

Published: Sept. 26, 2024, midnight
Mpox infection of stromal cells and macrophages of macaque with endometriosis.

The mpox outbreak of 2022-2023 represented a new global health challenge and recognition of mpox as a sexually transmitted disease. The majority of cases were reported in men who have …

Published: Sept. 20, 2024, midnight
Single-cell analysis identifies distinct macrophage phenotypes associated with prodisease and proresolving functions in the endometriotic niche.

Endometriosis negatively impacts the health-related quality of life of 190 million women worldwide. Novel advances in nonhormonal treatments for this debilitating condition are desperately needed. Macrophages play a vital role …

Published: Sept. 10, 2024, midnight
R-954, a bradykinin B1 receptor antagonist, as a potential therapy in a preclinical endometriosis model.

Endometriosis is a gynecological condition characterized by the growth of endometrium-like tissues outside of the uterine cavity. Currently available drugs are efficacious in treating endometriosis-related pain, however it's not a …

Published: Sept. 10, 2024, midnight
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