The human microbiota is increasingly recognized as a key component of women's reproductive health. This narrative review examines the vaginal, endometrial, and gut microbiota and their roles in the pathogenesis …
Does PIEZO1 play any role in adenomyosis-associated dysmenorrhea?
Endometriosis is a chronic inflammatory gynecological disease affecting approximately 10% of women of reproductive age and is associated with pelvic pain, infertility, and reduced quality of life. Increasing evidence suggests …
Background/Objectives: Endometriosis is a prevalent gynecological illness associated with chronic pain, inflammation, and infertility, as ectopic endometrial lesions are formed. No fully effective treatment is available, and the pathogenesis of …
Female reproductive disorders influence women's physical and mental well-being, and the sustainability of the family. However, it is unclear whether lifestyle factors, including sedentary behaviors and physical activity, could impact …
Professional societies recommend opportunistic salpingectomy during vaginal hysterectomy to reduce the risk of ovarian cancer, but it may be technically challenging without uterine prolapse. We examined national patterns, patient and …
To evaluate the efficacy and tolerability of the gonadotropin-releasing hormone antagonist elagolix for endometriosis-associated pain symptoms in adolescents and young adults (AYA).
Fibrosis, angiogenesis and chronic inflammation are the intrinsic characteristics of endometriosis. It is accompanied by significant changes in the cell composition of both ectopic and eutopic endometrial tissues, occurring both …
Endometriosis is a complex, estrogen-dependent disease with limited effective treatments that often focus on symptom management rather than addressing the underlying pathology. Current therapies, such as progestins and GnRH agonists, …
Endometriosis is a chronic gynecological disease associated with inflammation and severe pelvic pain in 6%-10% of women of reproductive age. Although the pathophysiology and management of endometriosis are currently understood, …