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S1P3 Receptor Mediates the Proinflammatory Effect of the Endocannabinoid 2-Arachidonoylglycerol in Endometriotic Epithelial Cells.

Endometriosis is a chronic inflammatory disease characterized by the ectopic implantation of endometrium outside the uterus associated with pelvic pain and infertility. The molecular mechanisms involved in the pathogenesis of …

Published: Nov. 27, 2025, midnight
May serum advanced oxidation protein products levels be diagnostic markers in endometrioma?

To evaluate the diagnostic utility of advanced oxidation protein products (AOPPs), calprotectin, and classical tumor markers (CA 125 and CA19-9) in distinguishing ovarian endometriomas from simple cysts and healthy controls, …

Published: Nov. 26, 2025, midnight
Pregnancy in women with advanced endometriosis and adenomyosis: possible complications and the role of surgery.

Advanced endometriosis (stage III-IV, per the revised American Society for Reproductive Medicine (rARSM) classification of endometriosis) is associated with a range of pregnancy-related complications. Despite growing evidence, awareness of these …

Published: Nov. 26, 2025, midnight
Massive serous cystadenofibroma with incidental umbilical endometriosis in a morbidly obese patient presenting as acute respiratory compromise.

We present a case of a woman in her 50s with a rapidly expanding giant serous cystadenofibroma of the ovary. The 40-kg mass displaced her bowel and splinted her diaphragm, …

Published: Nov. 24, 2025, midnight
Oxidative Stress-Telomere Axis in IVF: Molecular Mechanisms, Biomarkers, and Clinical Translation.

The reduction in oocyte competence and ovarian reserve coincides with reproductive ageing; nevertheless, the molecular mechanisms underlying this phenomenon remain poorly understood. Our testable mechanistic hypothesis is that the oxidative …

Published: Nov. 24, 2025, midnight
Umbilical Endometriosis: A Case Report.

Endometriosis is characterized by the ectopic presence of endometrial tissue outside the uterus. When this tissue appears in regions beyond the reproductive organs, it is referred to as extragenital endometriosis. …

Published: Nov. 24, 2025, midnight
Detection of peritoneal, ovarian, and bowel endometriosis using FTIR spectroscopy and machine learning.

This study evaluated the diagnostic potential of Fourier-transform infrared (FTIR) spectroscopy combined with machine learning for the detection of ovarian, bowel, and peritoneal endometriosis. The Boruta algorithm was applied to …

Published: Nov. 23, 2025, midnight
Progesterone and IL-6 Expression Are Modulated by Follicular Fluid in Granulosa Cell Cultures.

Endometriosis (ENDO) and poor ovarian response (POR) represent challenging conditions in assisted reproduction. Both, associated with altered follicular fluid (FF) composition, specifically impact on granulosa cell (GC) function in an …

Published: Nov. 23, 2025, midnight
THBS1 identificated as an endometriosis biomarker through evidence from single-cell and bulk transcriptomic profiling.

Endometriosis affects a substantial number of women of reproductive age, yet current diagnostic methods rely on invasive procedures. To address this limitation, we investigated THBS1 as a potential biomarker and …

Published: Nov. 21, 2025, midnight
A cross-sectional analysis of brain structure, pain behaviors, and mental health in persons with surgically confirmed endometriosis.

Endometriosis is a highly prevalent and often painful gynecological condition that can emerge in adolescence and can be experienced throughout a person's lifetime. This cross-sectional investigation performed structural brain imaging …

Published: Nov. 20, 2025, midnight
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