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Preliminary Evaluation of Leuprorelin Acetate Microspheres Plus Levonorgestrel-Releasing Intrauterine System in Endometriosis: An Exploratory Study Focusing on BNIP3 and EPAC1 Expression.

This exploratory pilot study aimed to assess the preliminary clinical effects of leuprorelin acetate microspheres for injection [gonadotropin-releasing hormone agonist (GnRH-a)] combined with levonorgestrel-releasing intrauterine system (LNG-IUS) in treating endometriosis …

Published: May 14, 2026, midnight
Exploring the mechanism of plastic additives on reproductive disorders based on network toxicology and molecular docking.

Phthalate esters (PAEs) and organophosphate esters (OPEs) are pervasive 20 environmental pollutants with endocrine-disrupting properties. Despite growing 21 evidence linking PAE/OPE exposure to female reproductive disorders, the 22 diseasespecific molecular …

Published: May 14, 2026, midnight
Diagnosis of Endometriosis: Dual-Amplification Strategy Driven by Copper Nanoclusters.

Endometriosis is a prevalent gynecologic disorder associated with infertility and increased cancer risk, necessitating the development of sensitive and reliable diagnostic methods. Circulating microRNAs (miRNAs) have emerged as promising noninvasive …

Published: May 14, 2026, midnight
Giant endometrioma of the canal of nuck mimicking a vulvar mass: a rare case and narrative review.

Endometriosis of the canal of Nuck is an extremely rare manifestation of extrapelvic endometriosis that may mimic common groin pathologies such as inguinal hernia or hydrocele, often leading to diagnostic …

Published: May 14, 2026, midnight
A single centre multidisciplinary team retrospective review of fifty cases of robot-assisted surgery for diaphragmatic and thoracic endometriosis.

Diaphragmatic and thoracic endometriosis (DTE) is considered rare, often presenting with non-specific cyclical thoracic symptoms. Diagnosis and surgical management remain challenging due to the need for cross-specialty expertise. This study …

Published: May 14, 2026, midnight
Sedentary behavior, physical activity, psychological well-being, and gynecologic and obstetric disorders: A multivariable Mendelian randomization and mediation analysis.

The independent causal effects of interrelated lifestyle behaviors and psychological states on women's gynecologic and obstetric health remain incompletely understood. We conducted a comprehensive Mendelian randomization (MR) study to disentangle …

Published: May 13, 2026, midnight
Dopamine D2 Receptor Agonists as Modulators of VEGF-A-Driven Angiogenesis: Mechanisms, Clinical Evidence, and Translational Opportunities.

Angiogenesis mediated by vascular endothelial growth factor A (VEGF-A) is essential for physiological vascular remodeling but also drives pathological processes, including tumor growth, ocular neovascularization, and inflammation. Emerging evidence has …

Published: May 13, 2026, midnight
Safety and efficacy of retromuscular-onlay dual-mesh reconstruction for massive abdominal wall defects secondary to abdominal wall endometriosis resection.

Massive abdominal wall defects resulting from radical abdominal wall endometriosis (AWE) resection present a major reconstructive challenge. This study aims to assess feasibility and short-term safety of a standardized retromuscular-onlay …

Published: May 13, 2026, midnight
TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour.

Female fertility relies heavily on the health of the oviduct and uterus. Each of these organs consist of a muscular tube lined by epithelial cells. In this review, we discuss …

Published: May 13, 2026, midnight
Application of 18F-FAPI PET/CT in Deep Infiltrating Endometriosis.

This case report demonstrates the enhanced visualization capabilities of FAPI in visualizing deep infiltrating endometriosis (DIE) lesions compared to ultrasonography and MRI, suggesting its potential as a powerful diagnostic tool …

Published: May 13, 2026, midnight
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