Latest Articles

Publication Date
Immunological Causes of Infertility: Diagnostic Perspectives.

From an immunological perspective, infertility mechanisms encompass not only fertilization but also implantation, as well as both early and late pregnancy loss. Growing attention is being directed towards the influence …

Published: Dec. 25, 2025, midnight
Identification and Subtype Analysis of Lipid Metabolism-Related Diagnostic Biomarkers for Endometriosis Based on WGCNA and Machine Learning.

Endometriosis (EM), a disorder driven by persistent systemic inflammation, impacts around 10% of women in their reproductive period, often diagnosed only via surgery. Metabolic alterations, particularly in lipid metabolism, may …

Published: Dec. 24, 2025, midnight
Targeting inflammation in endometriosis: emerging therapeutic options.

Endometriosis is a chronic, estrogen-dependent inflammatory disease affecting up to 10% of reproductive-aged women. Current therapies are predominantly hormone-based and offer symptomatic relief without correcting the immune dysregulation and inflammation …

Published: Dec. 24, 2025, midnight
The Histamine-Associated Inflammatory Landscape of Endometriosis: Molecular Profiling of HDC, HRH1-HRH4, and Cytokines Across Lesion Subtypes.

Pain in endometriosis involves not only nociceptive but also neuropathic and neurogenic components, reflecting its complex nature. Histamine, a biogenic amine, has emerged as a critical mediator connecting inflammation and …

Published: Dec. 24, 2025, midnight
MicroRNA Crossroads in PCOS and Endometriosis.

In the intricate landscape of health disorders in women, polycystic ovary syndrome and endometriosis stand out. Despite their complete etiology being unknown, their impact on women's health and link to …

Published: Dec. 23, 2025, midnight
Fertility preservation in endometriosis: current strategies and outcomes.

Endometriosis is a frequent chronic estrogen-dependent condition that can significantly impair fertility and reduce the quality of life in affected individuals. Women with endometriosis face a 30-50% risk of infertility. …

Published: Dec. 22, 2025, midnight
Endometriosis as an immune-mediated disease: pathogenetic mechanisms and therapeutic strategies.

Endometriosis, which affects approximately 10% of women of reproductive age, is a complex inflammatory disease with significant immune system disturbances caused by an inadequate immune response to retrograde menstruation and …

Published: Dec. 18, 2025, midnight
The Myth of Rectovaginal Septum Endometriosis: A Research Letter.

Endometriosis is a chronic condition where tissue resembling the uterine lining grows elsewhere in the pelvis, often causing pain, infertility, and inflammation. For decades, textbooks and research papers have described …

Published: Dec. 16, 2025, midnight
Delayed onset of HPV-associated uterine malignancies: seven pathogenetic factors in contrast to cervical cancer.

Human papillomavirus (HPV) is a well-established etiological agent for cervical cancer, yet its contribution to endometrial malignancies remains underrecognized and mechanistically distinct. This paper synthesizes current evidence to explain the …

Published: Dec. 13, 2025, midnight
Role of Phytoestrogens in Endometriosis.

To investigate the therapeutic potential of phytoestrogens in the management of endometriosis and to elucidate their mechanisms of action based on current preclinical and clinical evidence.

Published: Dec. 12, 2025, midnight
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