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Associations between aggregate index of systemic inflammation and endometriosis risk utilizing logistic regression analysis.

Systemic inflammatory response plays a key role in the pathogenesis of endometriosis. This study aimed to investigate the association between the aggregate index of systemic inflammation (AISI), defined as neutrophil …

Published: May 4, 2026, midnight
Electroacupuncture ameliorates Endometriosis-Associated ovarian dysfunction by activating Nrf2 pathway to upregulate GPX4 function and inhibiting ferroptosis.

Endometriosis (EMs) is a common cause of ovarian dysfunction and infertility, closely linked to iron overload-induced oxidative stress and ferroptosis. While electroacupuncture (EA) has shown promise in treating reproductive disorders, …

Published: May 3, 2026, midnight
"Effortful" motherhood: A mixed-methods study of the impact of endometriosis on family life.

Endometriosis can significantly affect family and intimate relationships. This mixed-methods study examined the impact of endometriosis on family life, with a focus on parenting. Women completed an online survey including …

Published: May 3, 2026, midnight
Quality of life among women of reproductive age during the accumulation of multiple chronic conditions.

We examined the temporal association between the number of chronic conditions and health-related quality of life (HRQOL) among women of reproductive age and assessed how individual conditions affected specific HRQOL …

Published: May 3, 2026, midnight
Terazosin as a Non-Hormonal Treatment for Endometriosis.

Endometriosis is a chronic, estrogen-dependent inflammatory disease including aberrant local steroidogenesis, inflammation, angiogenesis, oxidative stress, and prostaglandin-mediated pain. Given the elevated adrenergic receptor expression in endometriotic lesions and the potential …

Published: May 2, 2026, midnight
Sex-specific risk factors for stroke in women: Focus on the 2024 AHA/ASA guideline.

Women are less likely to have a stroke compared with men, but certain sex-specific risk factors can increase their risk for ischemic or hemorrhagic stroke later in life. The 2024 …

Published: May 1, 2026, midnight
Current methods and mechanisms for animal models of pelvic inflammatory disease: a review.

Pelvic inflammatory disease (PID) is a complex multifactorial infectious disorder of the female reproductive tract, associated with severe long-term sequelae including infertility, ectopic pregnancy, and chronic pelvic pain, as well …

Published: May 1, 2026, midnight
The enzymatic mechanisms of lactylation and its role in gynecological diseases: a comprehensive review.

Lysine lactylation (Kla) is a novel form of post-translational modification. It utilizes lactate as its core substrate. Through an enzymatic regulatory network, it mediates modifications of both histones and non-histone …

Published: April 30, 2026, midnight
Uterine and Sigmoid Colon Perforation Following Hysteroscopy-Guided Microwave Endometrial Ablation (MEA) in a Patient With a Bicornuate Uterus and Multiple Myomas: A Case Report.

In Japan, the microwave endometrial ablation system (MEA, Microsulis PLC, Waterlooville, UK) is the most widely used device for endometrial ablation and is considered a minimally invasive, uterus-preserving treatment for …

Published: April 29, 2026, midnight
Clinically Validated Leptin Receptor as a Target for Liposomal Delivery of Metformin in Endometriosis Therapy.

Endometriosis is a common, estrogen-driven chronic gynecologic disorder defined by the ectopic growth of endometrial-like tissue within the peritoneal cavity. Existing treatment options, primarily surgery and hormonal therapy, are limited …

Published: April 29, 2026, midnight
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