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Metabolomics Analysis Reveals Gut Microbiota-Associated Sakuranin Modulates Endometrial Stem Cell Differentiation and Inflammation to Alleviate Pain in Endometriosis [Letter].

Published: March 12, 2026, midnight
Novel approaches for PET imaging of endometriosis.

Endometriosis, affecting up to 10% of women, is a chronic estrogen dependent disorder where ectopic endometrial-like tissue causes pelvic pain and infertility. Endometriosis is challenging to diagnose due to symptom …

Published: March 12, 2026, midnight
sMICA/sMICB and Immune Checkpoint in Endometriosis: Toward a Minimally Invasive Diagnostic Model Based on Machine Learning.

Background: Endometriosis is a complex condition that impairs women's quality of life and reproductive potential. Its diagnosis remains significant challenge for clinicians. The aim of the study was to investigate …

Published: March 12, 2026, midnight
The #Enzian Classification as a Predictor of Hormonal Therapy Response in Endometriosis-Associated Pain: A Retrospective Cohort Study in a Referral Center.

To evaluate whether ultrasound-based #Enzian classification predicts pain profiles and response to hormonal therapy in patients with endometriosis. Endometriosis is a chronic inflammatory disease affecting 10% of reproductive-age women, often …

Published: March 11, 2026, midnight
Potential Harm of the Use of the Word "Benign" in Gynecologic Care.

"Benign gynecologic conditions" is an umbrella term widely used to describe prevalent conditions such as endometriosis, adenomyosis, uterine fibroids, and genitourinary syndrome of menopause in clinical guidelines, research, reviews, and …

Published: March 11, 2026, midnight
Beyond nociception: rethinking pain in ovarian endometriosis a pilot study.

Endometriosis affects 1 in 10 women, is the most common cause of chronic pelvic pain, classically known for its nociceptive pain mechanisms. Medical therapies have limited efficacy, prevent pregnancy, and …

Published: March 11, 2026, midnight
Association between estrogen receptor alpha 36 expression and the risk of deep infiltrating endometriosis.

Deep infiltrating endometriosis (DIE) is a severe subtype of endometriosis, often associated with dysmenorrhea and significant diagnostic challenges. Conventional biomarkers, such as cancer antigen 125 (CA125), lack sufficient specificity for …

Published: March 11, 2026, midnight
TRPM3 mediates spontaneous pain and mechanical allodynia in a mouse model of chronic orofacial neuropathy.

Trigeminal nerve injury can lead to chronic and difficult-to-treat orofacial neuropathic pain. Here, we uncover a key role for the cation channel TRPM3 in the chronic constriction injury of the …

Published: March 9, 2026, midnight
Hidden in the Scar: A Rare Case of Vulvar Endometriosis Mimicking Bartholin's Cyst at an Episiotomy Site.

Vulvar endometriosis is an exceptionally rare manifestation of extrapelvic endometriosis, particularly when located at the site of a prior episiotomy. Often misdiagnosed as more common vulvar pathologies, these lesions may …

Published: March 9, 2026, midnight
Global Trends in Endometriosis Burden, 1990-2021: A Sociodemographic Analysis Using GBD 2021 Data and Projections to 2036.

Endometriosis is a chronic inflammatory disorder that significantly compromises women's health, typically manifesting as pelvic pain and/or infertility. This condition imposes a substantial burden on global healthcare systems.

Published: March 9, 2026, midnight
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