Each year, over 700,000 pregnancies occur in the UK, with up to 10% affected by complications such as hypertensive disorders of pregnancy and gestational diabetes mellitus. Pregnancy-related complications and reproductive …
This study investigates the mechanism of Ge Xia-Zhu Yu decoction (GXZYT) in the treatment of endometriosis (EMS). The active components and targets of GXZYT were screened using TCMSP database and …
To develop and validate models to predict which endometriosis patients are likely to experience pain reduction following therapeutic laparoscopy using intraoperative findings and patient characteristics.
Multi-omics data are instrumental in obtaining a comprehensive picture of complex biological systems. This is particularly useful for women's health conditions, such as endometriosis which has been historically understudied despite …
Sex-related differences influence key biological processes relevant to biomaterials research, including tissue regeneration, immune response, drug metabolism, and relevant diseases. Despite increasing recognition of sex as a critical biological variable, …
To develop and validate a nomogram prediction model for chronic pain after hysterectomy for uterine fibroids.
Endometriosis is a common chronic gynecological condition that affects approximately 10% of women of reproductive age worldwide.
The immune system is hypothesized to contribute to the onset of endometriosis lesions. However, the precise mechanisms underlying its role are not yet known. We introduce a novel compartmental model …
In mammals, insulin-like peptide 3 (INSL3) and its cognate receptor (RXFP2) are reported to be essential regulators of male reproductive physiology. It is also believed that INSL3/RXFP2 signaling has a …
Endometriosis significantly impacts the quality of life (QoL) of affected women due to its complex symptomatology. This study aimed to develop a decision tree-based model to identify the key determinants …