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From polygenic risk to functional genomics: a framework for precision gynecological disease modeling.

Gynecological conditions including endometriosis, polyendocrine metabolic ovarian syndrome and malignancies cause widespread chronic morbidity and infertility, yet translating genetic discoveries into biological mechanisms remains challenging. We propose a framework integrating …

Published: Aug. 27, 2026, midnight
Transcriptome differences in lesions by color, and cancer mutations in endometriosis.

Endometriosis is a disease where cells similar to those of the uterine lining grow outside of the uterus, embedding into tissues and organs in the abdominal cavity, forming lesions and …

Published: Aug. 25, 2026, midnight
The role of SYNE1/2 variants as a potential predisposition factor for the onset of endometriosis.

Endometriosis (EM) is a chronic, inflammatory gynaecological disorder defined by the presence of endometrial-like tissue outside the uterine cavity, most frequently affecting the ovaries, peritoneum, and uterosacral ligaments. Despite its …

Published: Aug. 25, 2026, midnight
Comparative effectiveness of dienogest versus ethinyl estradiol/levonorgestrel combined oral contraceptive therapy in women with endometriosis-associated chronic pelvic pain.

To compare the clinical effectiveness of combined oral contraceptive pills (levonorgestrel-containing COC) and dienogest in the management of endometriosis-associated chronic pelvic pain and related symptoms.

Published: Aug. 25, 2026, midnight
Precise Surgical Navigation of Endometriosis via NIR-II Fluorescence Imaging With a Semiconducting Polymeric Probe.

Endometriosis is a prevalent gynecological disorder characterized by ectopic growth of endometrial-like tissue, often causing chronic pain, infertility, and systemic inflammation. Accurate detection and complete surgical resection remain challenging because …

Published: Aug. 24, 2026, midnight
Dyspareunia and heavy menstrual bleeding as clinical predictors of concomitant endometriosis in Inflammatory Bowel Disease: A multidisciplinary prospective study.

The association between Inflammatory Bowel Disease (IBD) and endometriosis is undefined.

Published: Aug. 24, 2026, midnight
The Effects and Mechanisms Underlying Red Meat Diet on Endometriosis Through Modulating Gut Microbiota.

Red meat consumption is widespread globally and has been associated with endometriosis (EMS) progression, although the precise underlying mechanisms remain unclear. In the present study, we aimed to explore the …

Published: Aug. 24, 2026, midnight
A comparative analysis of the pregnancy outcomes of IVF-ET in postoperative infertile patients with endometriosis treated with platelet-rich plasma and G-CSF: A retrospective cohort study.

This study aimed to investigate the impacts of granulocyte colony-stimulating factor (G-CSF) and platelet-rich plasma (PRP) on the pregnancy outcomes of infertile individuals with endometriosis after in vitro fertilization and …

Published: Aug. 23, 2026, midnight
Endometriosis-Related Chronic Pelvic Pain: Role of Integrated Supportive and Palliative Care (Letter-to-the-Editor).

Published: Aug. 22, 2026, midnight
A Large Secondary Umbilical Endometriosis (Villar's Nodule): A Case Report.

Umbilical endometriosis is a rare extrapelvic manifestation of endometriosis, presenting diagnostic and surgical challenges. We report a case of a 43-year-old woman with a history of two cesarean sections who …

Published: Aug. 22, 2026, midnight
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