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Kyobo Life Insurance has also released women-specific products as targeting women has emerged as an - 매일경제

Kyobo Life Insurance has also released women-specific products as targeting women has emerged as an 매일경제

Published: Oct. 10, 2025, 1:02 a.m.
NLRP3 Inflammasome in Gynecologic Inflammatory Diseases: Mechanisms, Pathophysiology, and Therapeutic Strategies.

The NOD-like receptor family containing pyridine domain 3 (NLRP3) inflammasome serves as a pivotal mediator of innate immune responses and a central driver of inflammatory processes. Upon detection of pathogenic …

Published: Oct. 10, 2025, midnight
TGFB1/SMAD3-Driven Macrophage-Myofibroblast Transition Promotes Fibrosis Progression in Endometriosis.

Endometriosis is a chronic gynecological disorder characterized by progressive fibrosis, which is closely associated with clinical symptoms such as dysmenorrhea and infertility. While myofibroblast activation is central to fibrogenesis, the …

Published: Oct. 7, 2025, midnight
Endometriosis-related infertility in China: analysis of the global burden of disease study 2021.

Utilizing the Global Burden of Disease (GBD) 2021 dataset, this study analyzed temporal trends (1990-2021) and age-period-cohort patterns of endometriosis-related infertility burden in China versus globally. By employing joinpoint regression …

Published: Oct. 7, 2025, midnight
Psychological, Symptom-Related, and Lifestyle Predictors of Health-Related Quality of Life in Hungarian Women with Endometriosis.

Background: This study was a cross-sectional online survey aimed at examining health-related quality of life and the effect of different symptoms and lifestyle factors on health-related quality of life in …

Published: Oct. 3, 2025, midnight
Targeting angiogenesis: Effects and mechanisms of action of ginsenosides.

Angiogenesis is a key link in a variety of physiological and pathological processes and plays a crucial role in tissue repair, tumor growth and ischemic diseases. Ginsenosides, as the main …

Published: Oct. 1, 2025, midnight
Analysis of diagnostic apoptosis-related biomarkers and immune cell infiltration characteristics in endometriosis by integrating bioinformatics and machine learning.

Endometriosis (EMs) is a chronic disease affecting millions of women worldwide, yet its pathogenesis remains unclear, and current diagnostic methods are limited. This study based on the EMs dataset from …

Published: Sept. 29, 2025, midnight
Dual Targeting of Orphan Nuclear Receptors NR4A1 and NR4A2 for Non-Hormonal Endometriosis Therapy.

Previous studies show that orphan nuclear receptor 4A1 (NR4A1) regulated endometriotic cell growth, survival, estrogen receptor β (ERβ), mTOR signaling and fibrosis. NR4A2 is also expressed in epithelial and stromal …

Published: Sept. 26, 2025, midnight
Regulated cell death in endometrial diseases: from molecular mechanisms to targeted therapies.

Regulated cell death (RCD) is a fundamental biological process essential for tissue homeostasis and disease regulation. Increasing evidence has demonstrated that RCD plays a pivotal role in the pathogenesis of …

Published: Sept. 22, 2025, midnight
Unravelling the Intricate Link: Mast Cells and Estrogen-Induced Pain Sensitization in Endometriosis.

Endometriosis is a prevalent gynaecological disorder characterized by estrogen-dependent lesions. Pain-particularly dysmenorrhea, chronic pelvic pain, and dyspareunia-is the hallmark symptom of endometriosis. While pain mechanisms remain poorly understood, mast cells …

Published: Sept. 21, 2025, midnight
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