Diseases of the female reproductive system are prevalent. These conditions often have a high proportion of asymptomatic patients and prolonged treatment durations. Estrogen, a crucial steroid hormone, plays a central …
Gynecologic disorders, such as cervical and ovarian tumors, uterine fibroids, and endometriosis, present significant clinical challenges due to frequent recurrence, emerging chemoresistance, and undesirable effects associated with prolonged hormonal treatments. …
Biomarkers and Immunotherapy in Endometrial Cancer: Mechanisms and Clinical Applications Frontiers
The ascent of novel alternative methods (NAMs) in drug development spotlights the dual needs for improved biological fidelity to in vivo along with reproducibility, especially in regulatory applications. The need …
Cystic adenomyosis is a rare subtype of adenomyosis characterized by cystic lesions within the myometrium, causing significant dysmenorrhea and pelvic pain. Traditional surgical treatments, such as laparoscopic or hysteroscopic excision, …
The immune system is crucial in protecting against disease, but it can also contribute to chronic illnesses when it malfunctions, with different conditions involving either inflammation or immune suppression. Current …
The aim of this study was to conduct a Hungarian cross-cultural adaptation and assess the reliability and validity of the Pelvic Pain Impact Questionnaire (PPIQ) in women with chronic pelvic …
There is a growing unmet need to digitalise the management of clinical data in medicine. Web-based scoring applications for endometriosis align with this trend.
The female reproductive system represents a highly complex regulatory network governing critical physiological functions, encompassing reproductive capacity and endocrine regulation that maintains female physiological homeostasis. The in vitro simulation system …
Acupoint Application Improves IVF Outcomes and Rescues Granulosa Cell Steroid Metabolic Dysregulation in Ovarian Endometriosis Frontiers