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Neurotrimin, a neural adhesion molecule, expression in early and advanced stage endometriosis.

Endometriosis, a gynecological condition characterized by the presence of endometrial tissue outside the uterus, affects millions of women worldwide. This study aimed to investigate neurotrimin (NTM)'s expression, a glycerophosphatidylinositol-anchored neural …

Published: Sept. 12, 2025, midnight
First documented case of decidualized endometriosis on the anterior peritoneum during emergency cesarean section: a case report and literature review.

Endometriosis is a chronic gynecological condition characterized by the presence of endometrial-like tissue outside the uterine cavity. Although commonly associated with pelvic pain and infertility, its incidental discovery during a …

Published: Sept. 8, 2025, midnight
Polychlorinated biphenyl Endocrine Disruptor Alters Estrogen Receptor beta-Mediated Epigenetic Regulation, Promoting Endometriosis.

Background Endometriosis is a pathological condition characterized by the ectopic proliferation of endometrial cells, resulting in chronic pelvic pain and infertility. Exposure to endocrine-disrupting chemicals (EDCs) has been implicated in …

Published: Sept. 4, 2025, midnight
Inhibition of VEGFR1 TK Signaling in Peritoneal Macrophages Suppresses Endometriosis Development.

Endometriosis is characterized by the accumulation of immune cells in endometrial lesions and the peritoneal cavity. Macrophages contribute to the growth and neovascularization of endometriotic lesions. Vascular endothelial growth factor …

Published: Aug. 30, 2025, midnight
Role of Transcription Factor, LIM Homeobox 9 (LHX9) in Inflammatory Response by PGE2 and Thrombin in SERPINA1-Silencing Endometrial Stromal Cells.

Endometriosis is hypothesized to result from retrograde menstruation where cell debris including endometrial stromal cells (ESCs) travel through the fallopian tubes. This chronic inflammatory disease is characterized by inflammatory and …

Published: Aug. 27, 2025, midnight
HOXC4 promotes proliferation of endometriotic stromal cells via the SLIT2-ROBO1 axis.

Current interventions for endometriosis mainly involve hormone therapies but have limited efficacy and unacceptable side effects due to the lack of selectivity to distinguish between endometriosis and endometrial tissues. Elucidating …

Published: Aug. 27, 2025, midnight
Analysis of menstrual effluent uncovers endometriosis-specific cell populations and impaired cellular pathway processes.

Endometriosis is a chronic gynecological disease affecting 1 in 10 reproductive-aged women and is characterized by the ectopic presence of endometrial tissue outside the uterus. The leading hypothesis for disease …

Published: Aug. 26, 2025, midnight
How transcription factors regulate apoptosis in endometriosis (Review).

Endometriosis (EM) is a common chronic gynaecological disease that affects 10% of women of reproductive age globally. EM is defined as the presence of endometrial glands and stroma in extrauterine …

Published: Aug. 24, 2025, midnight
Expression profiles of E-cadherin and N-cadherin in endometriosis and other gynecological diseases towards targeted treatment: a systematic review.

This systematic review aimed to summarize all available data and evaluate the roles of E-cadherin, N-cadherin, associated molecules, and signaling pathways in the pathogenesis of endometriosis. The search was conducted …

Published: Aug. 21, 2025, midnight
High levels of a comprehensive set of matrix metalloproteinases in endometriotic lesions: validating the key role of cellular senescence in endometriosis pathogenesis.

This study reveals elevated levels of MMP-1, MMP-2, and MMP-3 in endometriotic lesions, potentially reflecting a senescenceassociated secretory phenotype. No corresponding increase was observed in peritoneal fluid, possibly due to …

Published: Aug. 18, 2025, midnight
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