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MGST3 Promotes Endometriosis Progression by Suppressing Ferroptosis.

Endometriosis (EMs) is characterized by dysregulated persistence and enhanced invasiveness of ectopic endometrial cells. Current treatment strategies remain limited by high recurrence rates and considerable adverse effects. Although iron overload …

Published: June 3, 2026, midnight
Endometriosis at the extremes of reproductive life: A life-course perspective on age-specific phenotypes in adolescents and postmenopausal women.

To summarize current evidence on endometriosis in adolescents and postmenopausal women and to compare age-specific clinical characteristics, diagnostic approaches, and management strategies.

Published: June 3, 2026, midnight
Endometrial BCL6 Expression and Reproductive Outcomes in Infertile Women: A Systematic Review.

Background/Objectives: Endometrial B-cell lymphoma 6 (BCL6) overexpression has been proposed as a marker of progesterone resistance, occult endometriosis, and endometrial dysfunction in infertile women. Its possible association with reproductive outcomes …

Published: June 2, 2026, midnight
Association between adenomyosis subtypes and concurrent endometrial lesions: a propensity score-matched retrospective study.

Adenomyosis is increasingly recognized as a heterogeneous syndrome comprising focal and diffuse subtypes. While adenomyosis is known to be associated with endometrial lesions, it remains unclear whether this risk varies …

Published: May 29, 2026, midnight
Vitamin D deficiency and pain severity in endometriosis: a phenotype-based retrospective observational study.

To evaluate the association between serum 25-hydroxyvitamin D [25(OH)D] levels and pain severity in women with surgically and histopathologically confirmed endometriosis, and to assess whether this association differs between ovarian …

Published: May 28, 2026, midnight
Endometriosis and Chronic Endometritis: Shared Mechanisms, Diagnostic Challenges, and Clinical Implications in Infertility.

Endometriosis (EM) and chronic endometritis (CE) are both implicated in female infertility, yet the relationship between them remains incompletely understood. In this narrative review, we synthesize non-systematically selected clinical and …

Published: May 27, 2026, midnight
Parabacteroides goldsteinii and its metabolite 7-KLCA attenuate endometriosis via TGR5 to reprogram macrophages by modulating the PPARγ/GPR132 axis.

Endometriosis (EMS) remains understudied in effective management strategies. The interplay between macrophage dysfunction and microbiota-derived immune signals emerges as a potential mechanism in EMS pathogenesis, suggesting its relevance for future …

Published: May 22, 2026, midnight
ADVANTAGE: Advanced discovery of visceral analgesics by neuroimmune targets and the genetics of extreme human phenotype, a study protocol.

Chronic visceral pain affects over 20% of adults globally but remains poorly understood, significantly impacting quality of life and healthcare costs. Limited understanding and diagnostic misconceptions hinder effective management, particularly …

Published: May 21, 2026, midnight
Multi-omics Mendelian randomization integrating metabolism, microbiome and immunity supports a putative gut-immune-pelvic pathway in deep infiltrating endometriosis.

Deep infiltrating endometriosis (DIE) is a highly fibrotic and deeply invasive subtype of endometriosis that causes severe pelvic pain, infertility and marked impairment of quality of life. Metabolic, microbial and …

Published: May 21, 2026, midnight
The effects of endometrial polyps, leiomyomas, adenomyosis, and endometriosis on endometrial receptivity: phenotype, molecular pathways, and clinical implications.

This review synthesizes current evidence on how endometrial polyps, leiomyomas, adenomyosis, and endometriosis influence endometrial receptivity, emphasizing phenotype-specific effects, molecular mechanisms, and implications for embryo transfer outcomes.

Published: May 19, 2026, midnight
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