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Progesterone Receptor Status predicts Aggressiveness of Human Endometriotic lesions in Murine Avatars.

To utilize murine avatars for studying human endometriotic lesion response to two different hormonal regimens to determine if PR can prospectively predict response to progestin-based therapy. Endometriosis is a chronic …

Published: Oct. 9, 2024, midnight
Exploring the Role of MicroRNAs in Progesterone and Estrogen Receptor Expression in Endometriosis.

Background/Objectives: Patients with endometriosis still respond poorly to progestins due to progesterone resistance associated with microRNAs (miRNAs). The aim of this study was to investigate the expression of selected miRNAs, …

Published: Sept. 28, 2024, midnight
Effects, Doses, and Applicability of Gestrinone in Estrogen-Dependent Conditions and Post-Menopausal Women.

Gestrinone (R-2323), or ethylnorgestrienone, is a synthetic steroid of the 19-nortestosterone group more commonly used as an oral, intravaginal, or subcutaneous implant for the treatment of endometriosis, contraception, and estrogen-dependent …

Published: Sept. 22, 2024, midnight
Norethindrone-Associated Transaminitis in Endometriosis Patients: A Case Series and Literature Review.

In this case series, we discuss 10 cases of norethindrone-induced transaminitis and conduct a literature review of this rare adverse event. A retrospective chart review was conducted on 10 patients …

Published: Aug. 16, 2024, midnight
Levonorgestrel intrauterine system versus dienogest effect on quality of life of women with deep endometriosis: a randomized open-label clinical trial.

Women with deep infiltrating endometriosis (DIE) can benefit from the use of progestins. Our aim is to explore if levonorgestrel-releasing intrauterine system (LNG-IUS) non inferior to dienogest (DNG) in improving …

Published: Aug. 7, 2024, midnight
Phosphorylation of IDH1 Facilitates Progestin Resistance in Endometrial Cancer - Li - 2024 - Advanced Science - Wiley Online Library

Phosphorylation of IDH1 Facilitates Progestin Resistance in Endometrial Cancer - Li - 2024 - Advanced Science Wiley Online Library

Published: April 6, 2024, 7 a.m.
TSLP enhances progestin response in endometrial cancer via androgen receptor signal pathway - Nature.com

TSLP enhances progestin response in endometrial cancer via androgen receptor signal pathway Nature.com

Published: Jan. 3, 2024, 8 a.m.
Update on the management of endometriosis-associated pain in France.

The French National College of Obstetricians and Gynecologists (CNGOF) published guidelines for managing endometriosis-associated pain in 2018. Given the development of new pharmacological therapies and a review that was published …

Published: Sept. 3, 2023, midnight
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