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The role of mitophagy in female reproductive system diseases: from molecular mechanisms to therapeutic strategies.

Mitophagy is a catabolic mechanism that selectively degrades damaged mitochondria and precisely modulates mitochondrial content, thereby maintaining intracellular homeostasis under stress conditions. To date, most reviews on mitophagy have predominantly …

Published: Nov. 18, 2025, midnight
The Hugo™ RAS system in gynecologic robotic surgery: a systematic review of current applications.

The Hugo™ Robotic-Assisted Surgery (RAS) system is a recent development in minimally invasive gynecologic surgery. Following regulatory approval, its clinical use has expanded. However, comprehensive evidence on feasibility, safety and …

Published: Nov. 17, 2025, midnight
Cannabidiol and ∆9-Tetrahydrocannabinol in Endometriosis: A Literature Review on Therapeutic Applications and Mechanisms.

Endometriosis is a chronic, inflammatory, and multifactorial disease characterized by the presence of endometrial tissue outside the uterine cavity, often associated with debilitating symptoms. It affects approximately 10% of women …

Published: Nov. 17, 2025, midnight
Gene regulation by non-Coding RNAs in infertility: a mechanistic review.

Infertility is a significant global health issue affecting millions of couples, with noncoding RNAs (ncRNAs) emerging as pivotal regulators in reproductive biology. This review explores the roles of various ncRNAs, …

Published: Nov. 17, 2025, midnight
Endometriosis lesion growth inhibition and immune modulation function of thymol in vitro and in vivo.

Thymol, a phenolic monoterpene derivative found in the essential oil of Thymus vulgaris L., Lamiaceae, is currently under investigation for potential applications in pharmaceuticals, functional foods, and cosmetics. Despite ongoing …

Published: Nov. 17, 2025, midnight
Urogynecological Outcomes After Minimally Invasive Surgery for Deep Endometriosis: A Systematic Review.

Deep endometriosis (DE) frequently affects pelvic organs and may impair urinary function through both direct involvement and surgical nerve disruption. Minimally invasive excision is the standard treatment for symptomatic DE, …

Published: Nov. 17, 2025, midnight
Women with chronic pelvic pain can be stratified using multimodal assessment.

Chronic pelvic pain (CPP) is a common and burdensome symptom in women yet current clinical management frequently leaves many with persistent pain. The Translational Research in Pelvic Pain (TRiPP) project …

Published: Nov. 17, 2025, midnight
Circulating miRNA as diagnostic tools for gynecological diseases and their applications in biosensor development.

MicroRNAs (miRNAs) have emerged as robust biomarkers for diagnosing and prognosing gynecological diseases due to their disease-specific expression and remarkable stability in body fluids. Despite the inherent instability of RNA …

Published: Nov. 15, 2025, midnight
Robot-assisted resection of diaphragmatic and hepatorenal recess peritoneal endometriosis: Two cases and a narrative review.

In this report, we describe two cases of diaphragmatic endometriosis with concurrent hepatorenal recess peritoneal involvement managed using robotic-assisted laparoscopic surgery with the da Vinci Xi platform. In both patients, …

Published: Nov. 15, 2025, midnight
Unusual histopathologic findings of appendectomy specimens: A retrospective study of cases at Jordan University Hospital over the last decade (2015-2024).

To investigate the incidence and nature of unusual histopathological findings in appendectomy specimens and assess their impact on post-appendectomy management.

Published: Nov. 14, 2025, midnight
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