DRIVE-KG: Enhancing variant-phenotype association discovery in understudied complex diseases using heterogeneous knowledge graphs.
Multi-omics data are instrumental in obtaining a comprehensive picture of complex biological systems. This is particularly useful for women's health conditions such as endometriosis, which has been historically understudied despite …
Integrating ultrasound findings and extreme CA-125 elevation in the diagnosis of spontaneous endometrioma rupture: a case report.
Introduction: Spontaneous rupture of an endometrioma may result in life-threatening condition. Detection and prompt treatment are necessary. Presentation of Case: A 27-year-old woman presented to labor and delivery unit with …
Endometriomas are heterogeneous for functional FSH receptor expression and steroidogenic function.
We investigated whether ovarian endometriomas uniformly express functional FSH receptors (FSHR) and respond to FSH by activating transcriptional programs that drive aromatase and steroid hormone production. Endometrioma cyst capsules were …