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Case Report: Two clinical cases of severe deep infiltrating endometriosis with infertility-transplantation first or surgery first? Natural cycle or artificial cycle?

Deep infiltrating endometriosis (DIE) is a severe condition frequently linked to infertility, yet the optimal integration of surgery and assisted reproductive technology (ART) remains controversial. This study reports two cases …

Published: Dec. 16, 2025, midnight
Ultrasonic surgical aspiration (CUSA®) for laparoscopic excision of endometriosis: a prospective case series demonstrating safety and precision in fertility-preserving surgery.

Endometriosis affects ∼10% of women of reproductive age, often causing chronic pelvic pain and infertility. Conventional energy devices risk thermal injury and bleeding, particularly in fertility-preserving surgeries. The Cavitron Ultrasonic …

Published: Dec. 16, 2025, midnight
Compound design of a patient-derived 3D cell culture system modelling early peritoneal endometriosis.

Peritoneal endometriosis causes pelvic pain and infertility, but the underlying mechanisms related to these symptoms are not fully understood. Endometriosis diagnosis is typically delayed; thus, patient samples are unsuitable to …

Published: Dec. 15, 2025, midnight
Diagnostic discrepancies and clinical value of second medical opinions (SMO) for endometriosis: a nationwide study analysis.

Published: Dec. 15, 2025, midnight
Posterior Deep Infiltrating Endometriosis Surgery: current status and mapping of care in France.

Endometriosis is a frequent pathology affecting approximately 10% of the general population. Its diagnosis and management have improved in recent years. In France, a national strategy against endometriosis has been …

Published: Dec. 15, 2025, midnight
Is surgery for endometriomas ever indicated?

Endometriomas can be managed through various approaches, including careful observation, medical suppressive therapy, or surgical intervention. Malignancy is rarely a concern in women of reproductive age, making pain relief and …

Published: Dec. 15, 2025, midnight
Infiltrative Endometriosis Clinically Mimicking Ovarian Malignancy: Diagnostic Utility of Intraoperative Frozen Section.

Endometriosis is a benign gynecological condition that commonly affects women of reproductive age. It is characterized by the presence of ectopic endometrial tissue, predominantly within the pelvic cavity. Ovarian endometriosis …

Published: Dec. 14, 2025, midnight
Delayed onset of HPV-associated uterine malignancies: seven pathogenetic factors in contrast to cervical cancer.

Human papillomavirus (HPV) is a well-established etiological agent for cervical cancer, yet its contribution to endometrial malignancies remains underrecognized and mechanistically distinct. This paper synthesizes current evidence to explain the …

Published: Dec. 13, 2025, midnight
[Immunology of fertilization, implantation and pregnancy: Key interactions and therapeutic perspectives].

The immunology of fertilization, implantation and pregnancy is based on a complex balance between maternal immune tolerance and a controlled inflammatory response. Adaptation of the maternal immune system is essential …

Published: Dec. 13, 2025, midnight
Laparoscopic Management of Cystic Adenomyosis Complicated with Deep Infiltrating Endometriosis.

Published: Dec. 13, 2025, midnight
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