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Fertility preservation in endometriosis: evaluating surgical risks and emerging preservation approaches.

Endometriosis poses significant challenges for women of reproductive age, particularly due to its impact on ovarian reserve and fertility. In addition to endometriosis-associated infertility contributing to diminished ovarian reserve by …

Published: Aug. 16, 2025, midnight
Identification and Validation of Novel Combinatorial Genetic Risk Factors for Endometriosis across Multiple UK and US Patient Cohorts.

Endometriosis affects about 10% of women usually of reproductive age. It often has severe negative impacts on patients' quality of life, but the average time to a definitive diagnosis remains …

Published: Aug. 15, 2025, midnight
Detection of bacterial vaginosis-associated bacteria and outcomes during clinical gynaecological conditions using qPCR: A retrospective cohort study.

Endometriosis, chronic endometritis (CE), unexplained infertility (UI), and recurrent pregnancy loss (RPL) are gynecological conditions frequently associated with inflammation and alterations in the endometrial microbiome. The presence of bacterial vaginosis-associated …

Published: Aug. 15, 2025, midnight
AARS1 promotes endometriosis progression by promoting the lactylation of Snail1.

The widely accepted theory of endometriosis posits that endometriosis stems from the translocation of endometrial tissue through the fallopian tubes into the abdominal cavity. However, the exact pathogenesis and critical …

Published: Aug. 15, 2025, midnight
New therapeutic targets for endometriosis predicted through mendelian randomization analysis and case-control trials.

Endometriosis is a common chronic gynecological condition that affects approximately 10% of women of reproductive age worldwide.

Published: Aug. 15, 2025, midnight
Endometriosis and chronic pelvic pain management: Between a rock (denial) and a hard place (overdiagnosis).

Published: Aug. 14, 2025, midnight
Unveiling the vital role of OGG1 in inflammation, vascular endothelial damage, and cell death in obstetric and gynecological diseases.

The DNA repair enzyme 8-oxoguanine DNA glycosylase-1 (OGG1) plays a crucial role in the initiation of DNA base excision repair pathway by recognizing and excising the oxidative base lesions including …

Published: Aug. 14, 2025, midnight
Polypoidal rectal endometriosis-a diagnostic dilemma.

Polypoidal rectal endometriosis is a rare and diagnostically challenging manifestation of deep infiltrating endometriosis that may mimic colorectal malignancy, especially in women lacking classical cyclical symptoms. We report such a …

Published: Aug. 13, 2025, midnight
Mathematical modelling of macrophage and natural killer cell immune response during early stages of peritoneal endometriosis lesion onset.

The immune system is hypothesized to contribute to the onset of endometriosis lesions. However, the precise mechanisms underlying its role are not yet known. We introduce a novel compartmental model …

Published: Aug. 13, 2025, midnight
Efficacy and Safety of Personalized Percutaneous Single-Probe Cryoablation Using Liquid Nitrogen in the Treatment of Abdominal Wall Endometriosis.

Background: Abdominal wall endometriosis (AWE) is a rare but debilitating condition, often occurring in surgical scars after Caesarean sections. It is characterized by cyclic pain and a palpable mass, significantly …

Published: Aug. 13, 2025, midnight
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