Bioactive Compounds and Mechanistic Insights of Chuanxiong Rhizoma and Angelicae Sinensis Radix in Endometriosis Treatment: A Network Pharmacology and Experimental Validation Study.
Endometriosis, a chronic gynecological disorder, significantly impacts fertility and quality of life. Identifying effective therapeutic targets is critical for their management.
The Endometriosis Pain Course: exploring predictors of clinical response to an internet-delivered psychological pain management program for endometriosis.
Emerging research indicates the potential of psychological pain management programs to address disability and distress associated with endometriosis-related pain. Understanding the characteristics of patients likely to benefit from such programs …
Surgically confirmed severe endometriosis is associated with lower risk of steatotic liver disease: Evidence of estrogen-linked hepatic-reproductive crosstalk.
The prevalence of steatotic liver disease (SLD) is increasing globally. Endometriosis, affecting up to 10% of women, is a major cause of infertility. While associations between endometriosis and metabolic syndrome …
Anti-NRP1 peptide-engineered ROS/pH dual-responsive nanoparticles for Alpelisib delivery regulate Sema3A-NRP1/PI3K-AKT signaling to balance oxidative stress and inhibit angiogenesis in endometriosis.
Endometriosis progression is driven by oxidative stress and excessive angiogenesis within an inflammatory microenvironment. To overcome these challenges, we designed ROS/pH dual-responsive Alpelisib-loaded nanoparticles (Alp@TAT-AT7-NPs) functionalized with an anti-NRP1 peptide …