We present the rare case of a 29-year-old patient with uterine adenosarcoma who received fertility-sparing treatment, subsequently conceived spontaneously, and gave birth to a healthy infant.
Endometriosis is a chronic gynecological disease that can potentially develop as early as birth and can restrict the life of the patient. With the increasing prevalence of endometriosis in Germany, …
Endometriosis is an estrogen-dependent benign inflammatory disorder characterized by the implantation of active endometrial tissue (glands or stroma) outside the uterus, with pelvic adhesions as a core hallmark. Omental endometriosis …
Lactic acid modification of histones represents an emerging post-translational modification that establishes a critical link between cellular metabolic reprogramming and epigenetic regulation through the covalent binding of lactic acid to …
E-cigarette use (vaping) is rapidly increasing among women of reproductive age, with an estimated one in five women aged 15-45 now using e-cigarettes in England. Despite being promoted as a …
Menopause is a major global health issue affecting cisgender women, transgender people, and gender-diverse populations, yet it remains under-recognised in research and policy, particularly in low-income and middle-income countries. Rising …
To identify risk factors for dispensed opioid prescriptions after benign hysterectomy.
Gynecological diseases, such as polycystic ovary syndrome (PCOS) and endometriosis, are prevalent global health concerns. Conventional diagnostics often rely on invasive procedures or costly imaging, limiting accessibility in resource-constrained settings. …
Mineralocorticoid receptor antagonists, spironolactone, eplerenone, and finerenone, are cornerstone therapies in cardiovascular and renal diseases. While their efficacy is established, a systematic, head-to-head comparison of their post-marketing safety profiles based …
Three-dimensional (3D) endothelium-stromal co-cultures were established using human endometrial cells from biopsy of healthy women (n = 13) and serum samples from both healthy and endometriotic women (n = 5). …