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Saussurea lappa enhances folliculogenesis by suppressing F2-isoprostane, TNF-α, and apoptosis in endometriosis mice.

Endometriosis can disrupt folliculogenesis due to elevated levels of pro-inflammatory cytokines, free radicals, and the apoptotic response in granulosa cells (GCs). It can cause fertility issues in women. To date, …

Published: Sept. 30, 2025, midnight
Effectiveness and Safety of Postoperative Medical Treatments Following Fertility-Preserving Surgery for Endometriosis: A Network Meta-Analysis.

Endometriosis (EMs) is a common gynaecological condition with high recurrence rates after fertility-preserving laparoscopic surgery, and optimal postoperative medical treatment remains unclear.

Published: Sept. 29, 2025, midnight
Psychological factors mediate the relationship between trauma exposure and pain intensity in women with endometriosis: a cross-sectional study.

Endometriosis, a chronic inflammatory condition often characterized by chronic pelvic pain, significantly impacts women's quality of life. While psychological distress, including depression and anxiety, is prevalent in women with endometriosis, …

Published: Sept. 29, 2025, midnight
Analysis of diagnostic apoptosis-related biomarkers and immune cell infiltration characteristics in endometriosis by integrating bioinformatics and machine learning.

Endometriosis (EMs) is a chronic disease affecting millions of women worldwide, yet its pathogenesis remains unclear, and current diagnostic methods are limited. This study based on the EMs dataset from …

Published: Sept. 29, 2025, midnight
Pharmacogenomic analysis of alarelin acetate-induced hepatotoxicity: a case report and literature review.

Alarelin acetate, a synthetic gonadotropin-releasing hormone (GnRH) analogue, is widely used to manage endometriosis and hormone-sensitive malignancies. Although its safety profile is generally favorable, we report the first documented case …

Published: Sept. 29, 2025, midnight
Erythema ab igne-A Potential Cutaneous Marker of Chronic Heat Use in Patients with Endometriosis: A Narrative Literature Review and a Case Report.

Erythema ab igne (EAI), also known as "hot water bottle rash" or "toasted skin syndrome", is a benign cutaneous condition caused by chronic exposure to low-level infrared heat. It typically …

Published: Sept. 29, 2025, midnight
Influence of Complex Disease on the Accuracy of Transvaginal Ultrasound Diagnosis of Uterosacral Ligament Endometriosis.

To assess the impact of complex disease states, including pouch of Douglas (POD) obliteration and deep endometriosis (DE) of the bowel, on the diagnostic accuracy of transvaginal ultrasound (TVUS) for …

Published: Sept. 28, 2025, midnight
Clinicopathological Characteristics and Oncologic Outcomes of Endometrioid Ovarian Carcinoma: A Retrospective Study from a Tertiary Cancer Centre.

Background/Objectives: To evaluate the clinicopathological features, treatment, and survival outcomes and to identify independent prognosticators for recurrence and mortality in patients with endometrioid ovarian cancer. Methods: The medical records of …

Published: Sept. 28, 2025, midnight
Dual Targeting of Orphan Nuclear Receptors NR4A1 and NR4A2 for Non-Hormonal Endometriosis Therapy.

Previous studies show that orphan nuclear receptor 4A1 (NR4A1) regulated endometriotic cell growth, survival, estrogen receptor β (ERβ), mTOR signaling and fibrosis. NR4A2 is also expressed in epithelial and stromal …

Published: Sept. 26, 2025, midnight
Endometriosis Diagnostic Delay and Its Correlates: Results from the ComPaRe-Endometriosis Cohort.

Background: An average time to diagnosis of 7 years is commonly described for endometriosis; diagnostic delay for adenomyosis is unknown. This cross-sectional study aimed to describe diagnostic delay for endometriosis …

Published: Sept. 26, 2025, midnight
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