Urinary microRNAs for the non-invasive diagnosis of endometriosis identified by next-generation sequencing and machine learning.
Endometriosis is a chronic gynecological disease associated with pain, infertility, and delayed diagnosis. Non-invasive biomarkers are urgently needed to facilitate earlier detection and reduce the reliance on diagnostic laparoscopy. MicroRNAs …
Management of strangulated, perforated gastrothorax with resultant tension pneumothorax secondary to an iatrogenic diaphragmatic hernia: a case report.
Diaphragmatic hernias arise when a defect in the diaphragmatic musculotendinous framework allows the abnormal protrusion of abdominal contents into the thoracic cavity, which can be further complicated by visceral incarceration, …
Transcriptomic landscape of coexisting ovarian clear cell carcinoma and endometriosis: Insights into malignant transformation.
This study investigateted the malignant transformation of endometriosis (EMS) into ovarian clear cell carcinoma (OCCC) using spatial transcriptomics and single-cell RNA sequencing (scRNA-seq) integration. Tissues with coexisting EMS and OCCC …
Ginsenoside Rg3 antagonises endometriosis glycolysis via the tripartite motif containing 28 and pyruvate dehydrogenase kinase 4 signalling pathway.
Endometriosis is a common gynaecological disorder characterised by the ectopic growth of endometrial-like tissue, which can lead to clinical symptoms such as chronic inflammation, pelvic pain, and infertility. Aberrant cellular …