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R-954, a bradykinin B1 receptor antagonist, as a potential therapy in a preclinical endometriosis model.

Endometriosis is a gynecological condition characterized by the growth of endometrium-like tissues outside of the uterine cavity. Currently available drugs are efficacious in treating endometriosis-related pain, however it's not a …

Published: Sept. 10, 2024, midnight
Origin of Peritoneal Cancer With Features of High-grade Serous Carcinoma: A Detailed Molecular Analysis.

Primary peritoneal cancer has characteristics similar to high-grade serous carcinomas of ovarian and fallopian tube origin. However, the relationship between endometriosis and primary peritoneal cancer is not well understood. This …

Published: Sept. 10, 2024, midnight
Evidence of Browning and Inflammation Features in Visceral Adipose Tissue of Women with Endometriosis.

Patients with endometriosis tend to have a low body mass index, suggesting an inverse relationship between body fat and risk of disease. This is supported by evidence that miRNAs differentially …

Published: Sept. 7, 2024, midnight
The vicious cycle of chronic endometriosis and depression-an immunological and physiological perspective.

Endometriosis is a chronic, estrogen-dependent, proinflammatory disease that can cause various dysfunctions. The main clinical manifestations of endometriosis include chronic pelvic pain and impaired fertility. The disease is characterized by …

Published: Sept. 6, 2024, midnight
Catamenial hemothorax: a perplexing tale of unilateral hemothorax.

The clinical entity in which functional endometrial tissue is present in the thoracic cavity causing various clinical manifestations is called thoracic endometriosis syndrome (TES). Catamenial hemothorax (CHt) is a clinical …

Published: Aug. 2, 2024, midnight
The rs2046210 Polymorphism Is Associated with Endometriosis Risk and Elevated Estrogen Receptor 1 Expression in the Eutopic Endometrium of Women with the Disease.

In this focused genetic case-control study, we analyzed two functional single-nucleotide variants (SNVs) associated with breast cancer risk (rs2046210, rs9383590) and one risk SNV for an implantation defect and infertility …

Published: July 25, 2024, midnight
Genome-wide association reveals a locus in neuregulin 3 associated with gabapentin efficacy in women with chronic pelvic pain.

Chronic pelvic pain (CPP) in women with no obvious pelvic pathology has few evidence-based treatment options. Our recent multicenter randomized controlled trial (GaPP2) in women with CPP and no obvious …

Published: July 15, 2024, midnight
De novo reconstruction of a functional in vivo-like equine endometrium using collagen-based tissue engineering - Nature.com

De novo reconstruction of a functional in vivo-like equine endometrium using collagen-based tissue engineering Nature.com

Published: April 19, 2024, 7 a.m.
Rate and risk factors of inadequate endometrial tissues after endometrial sampling among Bhutanese women at the national referral hospital of Bhutan: a cross-sectional study - BioMed Central

Rate and risk factors of inadequate endometrial tissues after endometrial sampling among Bhutanese women at the national referral hospital of Bhutan: a cross-sectional study BioMed Central

Published: April 2, 2024, 7 a.m.
'Don't fob off severe period pains' Mum of two underwent five operations after endometriosis tissue spread - EVOKE

'Don't fob off severe period pains' Mum of two underwent five operations after endometriosis tissue spread EVOKE

Published: March 24, 2024, 7 a.m.
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