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Targeting the Wnt signaling network in endometriosis: mechanistic insights and translational opportunities.

Endometriosis is a chronic gynecological disorder defined by the growth of endometrial-like tissue outside the uterus, driven by estrogen-dependent inflammation and progressive fibrosis. According to available data, remodeling and persistent …

Published: May 8, 2026, midnight
A multi-dimensional computational screening strategy for rapid identification of active components from traditional chinese medicine: Validation and application in Liangdi decoction against endometriosis.

This study aims to develop and validate a Multi-Dimensional Computational Screening (MDCS) strategy to identify bioactive components by jointly considering target affinity, exposure potential, and safety, using Liangdi decoction (LDD) …

Published: May 8, 2026, midnight
Mortality risk associated with endometriosis: a systematic review and meta-analysis.

Endometriosis is a chronic, estrogen-dependent gynecological disorder affecting approximately 10% of women worldwide that can cause pelvic pain, lead to infertility, and impair quality of life. Whether the condition elevates …

Published: May 8, 2026, midnight
Neutrophil-to-lymphocyte ratio (nlr) as a predictor of endometriosis occurrence and prognosis: Evidence from a single-center study in Indonesia.

Endometriosis is a chronic inflammatory condition characterized by the presence of endometrial tissue outside the uterus, leading to pelvic pain and infertility. It affects approximately 10% of women of reproductive …

Published: May 8, 2026, midnight
Selected Parameters of the Mental State of Women with Endometriosis-A Systematic Review.

Background: Endometriosis is a chronic, estrogen-dependent inflammatory disorder affecting millions of women worldwide and constitutes a major cause of chronic pelvic pain and reduced quality of life. Increasing evidence suggests …

Published: May 8, 2026, midnight
A Narrative Review of Recent Insights on Nerve Growth Factor Signaling in Physiological and Pathological Ovarian Processes in Mammals.

Nerve Growth Factor (NGF), a member of the neurotrophin family, is currently regarded as a key regulator of ovarian physiology beyond its well-known neurotrophic functions. The mammalian ovary is one …

Published: May 8, 2026, midnight
Exploring the Genetic Influence of Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22) on Inflammatory Biomarkers in Endometriosis Progression.

Investigating the genetic influence of Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22) on key inflammatory biomarkers-Interleukin-1β, Interleukin-6, and high-sensitivity C-reactive protein (hsCRP) and to evaluate their association with disease progression …

Published: May 7, 2026, midnight
Diverging guidelines and consensus statements on preimplantation genetic testing for aneuploidy: indications and strategies reviewed.

Preimplantation genetic testing for aneuploidy (PGT-A) is widely used to screen for embryo aneuploidy, enabling the selection and transfer of genetically normal embryos. Despite its potential to improve clinical outcomes, …

Published: May 7, 2026, midnight
The main active monomer of Dan'e-fukang soft extract, liquiritin, inhibits the inflammation and invasion of ectopic endometrial stromal cells through down-regulation of CCL2.

The study explored the mechanism of Dan'e-fukang soft extract in treating endometriosis (EMs) through network pharmacology. The main active ingredients of Dan'e-fukang soft extract were analyzed based on the traditional …

Published: May 7, 2026, midnight
Business case for new regional endometriosis centre of excellence in Western Trust imminent - Derry Journal

Business case for new regional endometriosis centre of excellence in Western Trust imminent Derry Journal

Published: May 6, 2026, 9:42 a.m.
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