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NLRP1 promotes pyroptosis in endometriosis through the NF-κB signaling pathway.

Endometriosis is a prevalent gynecological disorder characterized by chronic inflammation. Pyroptosis, a type of programmed proinflammatory cell death, plays a crucial role in various inflammatory diseases. However, its specific mechanism …

Published: May 14, 2026, midnight
Sedentary behavior, physical activity, psychological well-being, and gynecologic and obstetric disorders: A multivariable Mendelian randomization and mediation analysis.

The independent causal effects of interrelated lifestyle behaviors and psychological states on women's gynecologic and obstetric health remain incompletely understood. We conducted a comprehensive Mendelian randomization (MR) study to disentangle …

Published: May 13, 2026, midnight
Dopamine D2 Receptor Agonists as Modulators of VEGF-A-Driven Angiogenesis: Mechanisms, Clinical Evidence, and Translational Opportunities.

Angiogenesis mediated by vascular endothelial growth factor A (VEGF-A) is essential for physiological vascular remodeling but also drives pathological processes, including tumor growth, ocular neovascularization, and inflammation. Emerging evidence has …

Published: May 13, 2026, midnight
Safety and efficacy of retromuscular-onlay dual-mesh reconstruction for massive abdominal wall defects secondary to abdominal wall endometriosis resection.

Massive abdominal wall defects resulting from radical abdominal wall endometriosis (AWE) resection present a major reconstructive challenge. This study aims to assess feasibility and short-term safety of a standardized retromuscular-onlay …

Published: May 13, 2026, midnight
Adoption of robot-assisted surgery for hysterectomy in France: a nationwide analysis of surgical routes and length of hospital stay (2020-2024).

Robot-assisted hysterectomy (RAH) has been progressively introduced in gynecologic surgery, yet nationwide data describing its uptake and early efficiency outcomes remain limited. We described trends in surgical route for hysterectomy …

Published: May 13, 2026, midnight
TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour.

Female fertility relies heavily on the health of the oviduct and uterus. Each of these organs consist of a muscular tube lined by epithelial cells. In this review, we discuss …

Published: May 13, 2026, midnight
Risk factors of ovarian cancer: a systematic review and meta-analysis of Mendelian randomiation studies.

Ovarian cancer (OC) remains a major global health issue, often diagnosed late and lacking effective screening.

Published: May 13, 2026, midnight
The role of the SIRT1/FOXO1 axis in regulating autophagy and inflammation in endometriosis.

Endometriosis, a common chronic gynecological disorder, involves cellular autophagy and inflammatory processes in its pathogenesis. However, the specific regulatory mechanisms of autophagy and inflammation in endometriosis remain unknown. In this …

Published: May 13, 2026, midnight
Trends and Characteristics of Inpatient versus Ambulatory Surgery for Endometriosis.

It is unknown to what degree surgical management of endometriosis occurs in outpatient ambulatory settings and what factors are associated with ambulatory versus inpatient surgical care.

Published: May 13, 2026, midnight
Application of 18F-FAPI PET/CT in Deep Infiltrating Endometriosis.

This case report demonstrates the enhanced visualization capabilities of FAPI in visualizing deep infiltrating endometriosis (DIE) lesions compared to ultrasonography and MRI, suggesting its potential as a powerful diagnostic tool …

Published: May 13, 2026, midnight
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