Steroidal alkaloids as multi-target therapeutics for the treatment of endometriosis.
Endometriosis is a chronic inflammatory disease characterised by ectopic endometrial tissue, progressive fibrosis and chronic pain, with a pathogenesis that goes beyond oestrogen dependence. The central question this review seeks …
Estetrol potentiates progesterone-driven growth restraint while blunting pro-angiogenic activation in murine endometriosis lesions.
Endometriosis is sustained by ectopic endometrial implants that remain proliferative and vascularized, making endocrine modulation a cornerstone of therapy. Estetrol (E4) an endogenous estrogen produced during pregnancy, with selective tissue …
Updated structured report for dynamic ultrasonography in patients with suspected or known endometriosis: Recommendations of the international society for gynecologic endoscopy (ISGE).
To update the 2021 International Society for Gynecologic Endoscopy (ISGE) recommendations for structured reporting of dynamic ultrasound findings in patients with suspected or known endometriosis, integrating recent technical and methodological …