Latest Articles

The role of gut microbiota in modulating estrogen in the inflammatory milieu of endometriosis: A molecular and pathophysiological perspective.

Endometriosis is a prevalent estrogen-dependent chronic inflammatory condition that affects millions of women of reproductive age worldwide. It is characterized by the growth of endometrial tissue outside the uterine cavity, …

Investigating Unilateral Ovarian Endometrioma's Effect on Ova and Embryo Quality in 409 Infertile Endometriotic Patients.

In women with unilateral endometriosis, how do ovarian endometriomas and their inflammatory content affect oocyte and embryo quality in affected versus healthy ovaries, and what is the impact on ART …

Epidemiological study and clinical consequences of endometriosis and PCOS co-occurrence in a clinical population of women: a cross-sectional study.

Fertility preservation in women with endometriosis: How, when, and for whom?

Fertility preservation options, including cryopreservation of oocytes, embryos, and ovarian tissue, were initially focused on women undergoing gonadotoxic chemotherapy for oncologic treatment. The indications have expanded to include nonmalignant conditions …

Primary Amenorrhea With Bilateral Endometriomas in a Teenager Girl With Cervical Hypoplasia and Vaginal Agenesis.

A rare case of primary amenorrhea caused by cervical hypoplasia and vaginal agenesis highlights the critical need for early diagnosis and timely surgical intervention to prevent severe complications such as …

Synergistic RU486 and olaparib therapy enhances apoptosis in endometriosis by simultaneously targeting hormonal signalling and DNA repair.

Endometriosis is a chronic, hormone-dependent disorder characterized by ectopic implantation of endometrial tissue, often accompanied by pain and infertility. Although the progesterone receptor modulator RU486 is effective for pain relief, …

The letrozole use in reproductive medicine: Beyond aromatase inhibition - a comprehensive review.

Letrozole and other aromatase inhibitors are increasingly recognized as first-line ovulation induction (OI) medications, offering an efficient and physiologic approach to ovarian stimulation that enhances outcomes in reproductive medicine. By …

A Dive into the Invisible: The Vaginal and Endometrial Microbiota in Gynecologic and Obstetric Disorders: A Narrative Review.

The human microbiota is increasingly recognized as a key component of women's reproductive health. This narrative review examines the vaginal, endometrial, and gut microbiota and their roles in the pathogenesis …

Reproductive outcomes after surgical correction of congenital obstructive genital tract anomalies: A systematic review and quantitative pooled analysis of published data.

Congenital obstructive genital tract anomalies are rare but clinically significant causes of menstrual outflow obstruction, endometriosis, and subfertility. Surgical correction aims to restore reproductive potential, yet evidence to guide counselling …

The Role of Nutrition on the Pathogenesis of Endometriosis.

Endometriosis is a chronic inflammatory gynecological disease affecting approximately 10% of women of reproductive age and is associated with pelvic pain, infertility, and reduced quality of life. Increasing evidence suggests …