Latest Articles

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Molecular Regulation of FOXO1 and Its Pathophysiological Significance in Endometriosis: A Narrative Review.

Endometriosis is a chronic inflammatory disorder that affects approximately 10% of women of reproductive age and exhibits tumor-like characteristics such as invasion, recurrence, and hormone-dependent proliferation despite its benign nature. …

Published: Dec. 19, 2025, midnight
Coexistence of endometriosis and inflammatory bowel disease: a case series and practical diagnostic review.

The objective of this review is to identify key clinical lessons and highlight diagnostic and therapeutic strategies derived from case reports and recent literature. Particular attention is given to recognising …

Published: Dec. 18, 2025, midnight
Endometriosis as an immune-mediated disease: pathogenetic mechanisms and therapeutic strategies.

Endometriosis, which affects approximately 10% of women of reproductive age, is a complex inflammatory disease with significant immune system disturbances caused by an inadequate immune response to retrograde menstruation and …

Published: Dec. 18, 2025, midnight
[Immunology of fertilization, implantation and pregnancy: Key interactions and therapeutic perspectives].

The immunology of fertilization, implantation and pregnancy is based on a complex balance between maternal immune tolerance and a controlled inflammatory response. Adaptation of the maternal immune system is essential …

Published: Dec. 13, 2025, midnight
Burrowing behavior is a potential non-invasive proxy for lesion development in a syngeneic murine model of endometriosis.

Endometriosis (EM) is a persistent, chronic inflammatory condition associated with excruciating pelvic pain and infertility. The absence of a pre-clinical model that reliably replicates the clinical and functional hallmarks of …

Published: Dec. 12, 2025, midnight
Endometriosis: Pathophysiology and the Potential Role of Diet.

Endometriosis (ENDO) is a chronic, estrogen-dependent condition affecting over 190 million females worldwide. Characterized by cyclic pelvic pain, infertility, and systemic inflammation, its symptoms profoundly impact quality of life, interfering …

Published: Dec. 12, 2025, midnight
Bidirectional causal relationship between inflammatory cytokines and endometriosis at different sites.

This study aims to explore the genetic connection between inflammatory cytokines (IC) and endometriosis (EMs) to provide insights for the treatment of EMs.

Published: Dec. 9, 2025, midnight
Online Cognitive-Behavioral Programs for Women Living With Endometriosis: Protocol for a Scoping Review.

Endometriosis is a chronic inflammatory condition experienced by approximately 10% of women worldwide. Women living with endometriosis experience multidimensional burdens often attributed to pain, fatigue, anxiety, and depression. Treatment patterns …

Published: Dec. 8, 2025, midnight
IMPACT OF ENDOMETRIOSIS ON THE PROGRESSION OF INFLAMMATORY BOWEL DISEASES: A MULTICENTER RETROSPECTIVE STUDY.

Women with endometriosis have a higher risk of developing inflammatory bowel diseases (IBD). This study aimed to better understanding the impact of endometriosis on the course of IBD.

Published: Dec. 8, 2025, midnight
Microvascular hypoxia and inflammation in chronic pain syndromes.

In this opinion, we propose that compromised microvascular perfusion and inflammation are fundamental drivers of chronic pain syndromes, with many of these conditions sharing a common etiology involving suboptimal blood …

Published: Dec. 8, 2025, midnight
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