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Exploration of driver biomarkers and immune microenvironment in patients with endometriosis: Evidence from RNA-seq and machine learning.

Endometriosis (EM) is a condition that impacts roughly 10% of women within the reproductive age demographic on a global scale. Due to the limitations of conventional diagnostic techniques for endometriosis, …

Published: March 9, 2026, midnight
Endometriosis at the Single-Cell Level: Molecular Insights and Implications for Assisted Reproduction Success.

Endometriosis is a chronic hormone-responsive disorder linked to infertility, usually characterized by the presence of ectopic endometrium in the pelvis that disrupts local homeostasis. Advances in single-cell "omic" methods have …

Published: March 9, 2026, midnight
The effect of endometriosis on fertility: Results of the National Health and Nutrition Examination and Mendelian randomization analysis, 1999 to 2006.

This study aims to investigate the effect of endometriosis (EMs) on fertility and to assess the causal relationship between EMs and fertility using two-sample Mendelian randomization (MR). We conducted an …

Published: March 7, 2026, midnight
From lipid profiles to disease onset: Triglycerides as predictive biomarkers in endometriosis.

Dyslipidaemia is related to endometriosis, but it is not known which lipid component is most relevant, and whether the observed correlation reflects the causal relationship. The relationship between triglycerides (TG) …

Published: March 7, 2026, midnight
Comparison of Letrozole with Elagolix for the Management of Endometriosis-Associated Pain: A Quasi-Experimental Study.

To compare the efficacy of Letrozole and Elagolix in the medical management of endometriosis-associated pain Study Design: A quasi-experimental study. Place and Duration of the Study: Department of Obstetrics and …

Published: March 6, 2026, midnight
Effects of E2/ERβ on follicular granulosa cells and on AMH/Smad signalling in endometriosis.

Patients with endometriosis have greater risk of infertility, which is associated with compromised ovarian function. Dysfunction in follicular granulosa cells and hyperactivation of oestrogen receptor beta (ERβ) are evident in …

Published: March 6, 2026, midnight
Bridging Clinical Care and Self-Management: Impact of Nursing Module Based on WHO's Universal Self-Care Framework in Women with Endometriosis.

Aims: This study aims to assess the effect of a structured universal self-care practices module on improving self-care compliance and health maintenance behaviors among women with endometriosis, and to determine …

Published: March 6, 2026, midnight
Vaginal estrogen therapy not associated with increased risk of endometrial cancer recurrence - Contemporary OB/GYN

Vaginal estrogen therapy not associated with increased risk of endometrial cancer recurrence Contemporary OB/GYN

Published: March 5, 2026, 12:23 a.m.
TCF21 promotes epithelial-to-mesenchymal transition and cytoskeleton reorganization in uterine development and endometriosis.

Endometriosis is a common gynecological disease associated with pelvic pain and infertility. Despite several existing theories, the etiology and molecular mechanisms of endometriosis remain to be investigated. Here we report …

Published: March 5, 2026, midnight
Lactoferrin as a Non-Hormonal Therapeutic Candidate for Endometriosis: Mechanisms and Future Directions.

The pathogenesis and progression of endometriosis may involve a complex combination of multiple factors, including chronic inflammation and oxidative stress. Hormonal therapy, the current standard for pharmacotherapy in endometriosis, causes …

Published: March 5, 2026, midnight
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