Endocrine dysfunctions refer to alterations in hormone production, release, or regulation that can significantly impact health. In pregnant women or those planning pregnancy, these conditions may manifest as disorders such …
Di(2-ethylhexyl) phthalate (DEHP), the most prevalent plasticizer worldwide, can enter the human body via various exposure pathways, including ingestion, inhalation, skin contact, and medical applications. It has been observed to …
Endometriosis disease affects up to 10 % of menstruating people worldwide and can lead to infertility. Environmental pollutants are risk factors influencing the probability of developing endometriosis.
In mammals, insulin-like peptide 3 (INSL3) and its cognate receptor (RXFP2) are reported to be essential regulators of male reproductive physiology. It is also believed that INSL3/RXFP2 signaling has a …
Phthalate metabolites Mono- (2-ethylhexyl) phthalate(MEHP) and Phthalic Acid Monobenzyl Ester (MBZP) are widely present in the environment, can interfere with the endocrine system and accumulate in human tissues, and are …
Globally, endometriosis affects almost 10% of reproductive-aged women, leading to chronic pain and discomfort. Endocrine-disrupting compounds (EDCs) seem to play a pivotal role as a causal factor. The current manuscript …
Endometriosis (EMS) significantly impacts women's health and is influenced by genetic factors and environmental endocrine-disrupting chemicals (EDCs), which interfere with hormonal balance. Using the Gene Expression Omnibus database, we identified …
Synthetic sex hormones, estrogens and/or progestogens, have been widely administered without sufficient long-term studies for decades to millions of pregnant women around the world and although most were banned in …
Glyphosate-based herbicides (GBHs) are the most widely used herbicides in the United States, accounting for 19% of estimated global use. Although the Environmental Protection Agency (EPA) has reaffirmed that the …
Endometriosis is a debilitating condition characterized by the growth of endometrial-like tissue outside the uterus, leading to chronic pain and inflammation. While its etiology remains complex, emerging evidence implicates environmental …