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Causal associations between sleep disorders and endometriosis: A Mendelian randomization analysis.

Evidence have indicated a correlation between sleep disorders and endometriosis, but the causal relationship remains uncertain. This study utilized Mendelian randomization (MR) approach to investigate the causal associations between sleep …

Published: Nov. 10, 2025, midnight
Case Report: Diagnostic challenges in cervical small cell neuroendocrine carcinoma of a reproductive-age woman.

Small cell neuroendocrine carcinoma of the cervix (SCNEC) is a rare and highly aggressive malignancy with a poor prognosis. We report the case of a 36-year-old nulliparous woman with a …

Published: Nov. 10, 2025, midnight
Analysis of Risk Factors Associated With Persistent Noncyclic Pelvic Pain Despite Hormonal Treatment in Patients With Endometriosis.

To identify risk factors that predict the persistence of noncyclical pelvic pain in patients with endometriosis despite receiving hormone therapy.

Published: Nov. 9, 2025, midnight
A Case of Appendiceal Endometriosis Diagnosed as Acute Appendicitis and Treated With Laparoscopic Appendectomy.

Appendiceal endometriosis is an uncommon manifestation of extrapelvic endometriosis that can clinically and radiologically mimic acute appendicitis. We report the case of a 41-year-old woman who presented with acute right …

Published: Nov. 9, 2025, midnight
Analysis of Nociceptive Pain and Related Psychosocial Factors in Women With Endometriosis: A Cross-sectional Study.

The purpose of this study was to explore the associations and compare differences in abdominal and lumbar pain pressure thresholds, pelvic floor state, and pain- and movement-related psychosocial factors in …

Published: Nov. 7, 2025, midnight
Presacral Clear Cell Carcinoma of Müllerian Origin 20 Years After Hysterectomy and Bilateral Salpingo-Oophorectomy: A Case Report and Literature Review.

Primary presacral clear cell carcinoma (CCC) of Müllerian origin is extremely rare. Malignant transformation of endometriosis is a known phenomenon, though typically involving the ovaries or pelvic peritoneum. Retroperitoneal presentation, …

Published: Nov. 7, 2025, midnight
Associations of PFAS exposure with obstetric and birth outcomes in the Japan Environment and Children's Study (JECS): Is maternal endometriosis an effect modifier?

Per- and polyfluoroalkyl substances (PFAS) are reportedly associated with adverse obstetric outcomes, including premature labor and gestational diabetes. We aimed to evaluate associations of maternal PFAS exposure with obstetric and …

Published: Nov. 6, 2025, midnight
Sonographic and Clinical Progression of Adenomyosis and Coexisting Endometriosis: Long-Term Insights and Management Perspectives.

Objectives: To evaluate the impact of hormonal therapy on the evolution of painful symptoms in premenopausal women with adenomyosis, with or without concomitant endometriosis, over an 18-month follow-up period. This …

Published: Nov. 6, 2025, midnight
Metabolome analysis as a potential source of endometriosis biomarkers with the use of multiomics approach in its diagnosis.

Endometriosis poses diagnostic challenges. This study aimed to analyze the metabolomic profiles of plasma and peritoneal fluid samples obtained from women with endometriosis compared to controls. Our multicenter study involved …

Published: Nov. 5, 2025, midnight
Altered miR-410-3p and Target Genes (PCDH8, VEGFA, NUMB) Expression in Ovarian Endometriosis: A Case-Control Study.

Endometriosis is a condition in which tissue similar to the endometrium grows outside the uterus. Angiogenesis plays an important role in endometriosis development. Bioinformatics analysis indicates that miR-410-3p is involved …

Published: Nov. 5, 2025, midnight
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