Latest Articles

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Dysregulated autophagy in endometriosis: molecular mechanisms, controversies, and clinical implications.

Endometriosis is one of the most common gynecological diseases in women and is still one of the most understudied diseases, affecting the daily lives of patients. Although the exact cause …

Published: Dec. 13, 2025, midnight
Mechanism of FOXC1 in the invasion and migration of ectopic endometrial stromal cells in endometriosis.

Published: Dec. 13, 2025, midnight
Role of Phytoestrogens in Endometriosis.

To investigate the therapeutic potential of phytoestrogens in the management of endometriosis and to elucidate their mechanisms of action based on current preclinical and clinical evidence.

Published: Dec. 12, 2025, midnight
The interplay between migraine, endometriosis and polycystic ovarian syndrome: A systematic review.

BackgroundMigraine and gynecological conditions, such as endometriosis (EDM) and polycystic ovarian syndrome (PCOS), are highly prevalent among females and appear to influence each other, with a potential shared pathophysiological mechanism. …

Published: Dec. 12, 2025, midnight
Endometriosis: Pathophysiology and the Potential Role of Diet.

Endometriosis (ENDO) is a chronic, estrogen-dependent condition affecting over 190 million females worldwide. Characterized by cyclic pelvic pain, infertility, and systemic inflammation, its symptoms profoundly impact quality of life, interfering …

Published: Dec. 12, 2025, midnight
Iron: A double-edged sword of female reproductive health.

Iron is an essential micronutrient element for human. It participates in energy metabolism, enzyme activation, immune system and other metabolic functions. In this review, the potential role of iron in …

Published: Dec. 11, 2025, midnight
Microvascular hypoxia and inflammation in chronic pain syndromes.

In this opinion, we propose that compromised microvascular perfusion and inflammation are fundamental drivers of chronic pain syndromes, with many of these conditions sharing a common etiology involving suboptimal blood …

Published: Dec. 8, 2025, midnight
From Inflammation to Malignancy: The Link Between Endometriosis and Gynecological Cancers.

Endometriosis, a chronic estrogen-dependent disease, is associated with a risk of developing gynecological cancers. The mechanisms of this association remain unclear, but emerging evidence implicates key signaling pathways, including PI3K/AKT/mTOR …

Published: Dec. 7, 2025, midnight
UBE2S-mediated deubiquitination of GLUT1 via USP10 regulates glucose metabolic reprogramming and immune microenvironment to promote fibrosis in endometriosis.

Endometriosis (EM) is a chronic inflammatory disorder characterized by the growth of ectopic endometrial-like tissue and fibrosis. Metabolic reprogramming, particularly enhanced glycolysis, and immune microenvironment dysregulation are key features of …

Published: Dec. 5, 2025, midnight
Sun's Bushen Huayu Formula Restores Fertility in Endometriosis by Modulating Th1 and Th2 Cytokine Balance in Clinical and Animal Models.

Endometriosis (EMs) is a common gynecological disorder frequently associated with infertility, yet the underlying immune mechanisms remain poorly understood. Sun's Bushen Huayu Formula (BSHYF) has been clinically applied to improve …

Published: Dec. 5, 2025, midnight
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