Endometriosis-derived iPSCs reveal conserved stromal maturation and endocrine responsiveness.
Endometriosis is a chronic, hormone-dependent disease characterized by altered endometrial stromal function, but mechanistic and translational studies have been hindered by the lack of tractable human models. Here, we establish …
Identification of potent inhibitors of JUN N-terminal kinases for treatment of endometriosis and associated pain.
Endometriosis, defined as the ectopic growth of endometrial tissue outside of the uterine cavity, is an inflammatory and hormone-dependent disease that causes excruciating pelvic pain, infertility, and significantly decreases quality …
Endometriosis-associated bone loss: re-evaluating the potential role of systemic inflammation and hypoestrogenic therapies.
Endometriosis is frequently managed with hormonal suppression that can induce hypoestrogenism during a period when many patients are still accruing peak bone mass. This narrative review summarizes current clinical and …
Effect of Endometriosis on Surgical Outcomes of Total Laparoscopic Hysterectomy for Benign Indications: A Propensity Score-Matched Analysis.
The objective of the study was to retrospectively evaluate the impact of endometriosis on perioperative outcomes in patients undergoing total laparoscopic hysterectomy (TLH) for benign diseases.