Endometriosis, traditionally viewed as a gynecological condition, is increasingly recognized as a systemic disease due to its frequent association with inflammatory and autoimmune comorbidities. Recent molecular and genetic insights reveal …
This FIGO committee opinion paper addresses the growing body of evidence linking environmental exposures to common gynecologic and reproductive conditions across the life course. From adolescence through menopause, women are …
Endometriosis is a common gynecologic condition that causes chronic, life-altering symptoms including pain and infertility. There is an urgent need for new non-hormonal targeted therapeutics to treat endometriosis, but until …
Endometriosis is a complex gynecological condition affecting 10% of women globally, characterized by the growth of endometrial-like tissue outside the uterus, leading to chronic pelvic pain, infertility, reduced quality of …
Endometriosis is an estrogen-dependent disorder with unclear molecular mechanisms. Ferroptosis, a regulated iron-dependent cell death, may play a key role, yet the specific genes involved remain underexplored.
Endometriosis affects about 10% of women usually of reproductive age. It often has severe negative impacts on patients' quality of life, but the average time to a definitive diagnosis remains …
The immune system is hypothesized to contribute to the onset of endometriosis lesions. However, the precise mechanisms underlying its role are not yet known. We introduce a novel compartmental model …
A well-differentiated endometrioid carcinoma at the site of extra-uterine/ovarian endometriosis complicates the differentiation between an uncommon metastatic pattern from a corpus cancer and a synchronous primary tumor originating from adjacent …
The molecular mechanisms through which endometriosis-related ovarian neoplasms (ERONs) develop from benign endometrioma remain unclear. It is especially a long-standing mystery why ovarian endometrioma has the potential to develop into …
The relationship between poverty and tuberculosis (TB) is well-documented, as socio-economic deprivation constitutes a risk factor that drives TB transmission and progression while hindering treatment adherence. Despite the importance of …