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Safety evaluation of a novel progesterone vaginal ring (PVR) for luteal phase support: SARA trial.

After manufacturing changes, the safety and tolerability of the progesterone vaginal ring (PVR) was compared to findings from the similarly designed phase 3 trial. This prospective, open-label, single-arm, multi-center U.S. …

Published: May 29, 2026, midnight
The Microbiota-Endometriosis Axis: An Immune-Endocrine Integration Model and Emerging Therapeutic Targets.

Endometriosis is a chronic, estrogen-dependent inflammatory disorder characterized by the ectopic implantation and persistence of endometrial-like tissue outside the uterine cavity. Despite its high prevalence and significant impact on quality …

Published: May 28, 2026, midnight
Citizen science reveals comorbidities in endometriosis with no shift in vaginal microbiome composition.

Endometriosis is a chronic inflammatory condition affecting 2-10% of reproductive-aged women, most commonly presenting with pelvic pain and subfertility. While its impact on reproductive health is increasingly recognized, the vaginal …

Published: May 27, 2026, midnight
Artificial intelligence potential in ovarian endometriosis imaging: a comparative meta-analysis of transvaginal ultrasound-based AI models and human readers.

Transvaginal ultrasound (TVUS) is widely used for diagnosing ovarian endometriosis but remains limited by significant operator dependency. This systematic review and meta-analysis evaluated the diagnostic accuracy of ultrasound-based artificial intelligence …

Published: May 26, 2026, midnight
Acute and chronic complications of cesarean delivery: An update for the general radiologist.

Cesarean section has become a frequent mode of delivery in the last few decades. While generally regarded as a safe procedure, it is not free of potential complications, often requiring …

Published: May 25, 2026, midnight
Correlations Between Ultrasound Features and Histological Findings in Adenomyosis: A Single-Center Retrospective Study.

Adenomyosis is a benign gynecologic condition characterized by ectopic endometrial glands and stroma present within the myometrium. Background/Objectives: The gold standard in diagnosis is the histology of hysterectomy specimens. Due …

Published: May 22, 2026, midnight
ADVANTAGE: Advanced discovery of visceral analgesics by neuroimmune targets and the genetics of extreme human phenotype, a study protocol.

Chronic visceral pain affects over 20% of adults globally but remains poorly understood, significantly impacting quality of life and healthcare costs. Limited understanding and diagnostic misconceptions hinder effective management, particularly …

Published: May 21, 2026, midnight
Mixed tumor of the vagina with atypical features: a case report including clinical management.

To present a rare case of mixed vaginal tumor with atypical features and to discuss clinical management in the context of uncertainty regarding biological behavior.

Published: May 20, 2026, midnight
A nomogram integrating a novel uterine isthmus ratio (APTUIR), sonographic signs and clinical symptoms for predicting posterior deep endometriosis.

This study aims to propose a novel, reproducible transvaginal ultrasound (TVUS) measurement-anterior-posterior wall thickness of the uterine isthmus ratio (APTUIR)-and to construct a nomogram model integrating this parameter with other …

Published: May 18, 2026, midnight
Selective temporary protective loop ileostomy in complex rectal resection for deep infiltrating endometriosis: a prospective matched cohort study on bowel function, quality of life, and postoperative complications.

This study aimed to evaluate the impact of temporary protective loop ileostomy (PLI) on postoperative complications, bowel function, and quality of life (QoL) in women undergoing rectal surgery for deep …

Published: May 18, 2026, midnight
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