The ascent of novel alternative methods (NAMs) in drug development spotlights the dual needs for improved biological fidelity to in vivo along with reproducibility, especially in regulatory applications. The need …
A woman in her 30s presented to the emergency department with a one-day history of acute lower abdominal pain, which was not related to her menstruation and not associated with …
Ovarian endometrioma (OMA), the most prevalent and clinically consequential subtype of endometriosis, represents a chronic inflammatory disorder characterized by ectopic endometrial-like lesions. This condition manifests as progressive dysmenorrhea, ovarian reserve …
Cystic adenomyosis is a rare subtype of adenomyosis characterized by cystic lesions within the myometrium, causing significant dysmenorrhea and pelvic pain. Traditional surgical treatments, such as laparoscopic or hysteroscopic excision, …
The immune system is crucial in protecting against disease, but it can also contribute to chronic illnesses when it malfunctions, with different conditions involving either inflammation or immune suppression. Current …
The aim of this study was to conduct a Hungarian cross-cultural adaptation and assess the reliability and validity of the Pelvic Pain Impact Questionnaire (PPIQ) in women with chronic pelvic …
Background: This study was a cross-sectional online survey aimed at examining health-related quality of life and the effect of different symptoms and lifestyle factors on health-related quality of life in …
Advanced pelvic surgeries, such as radical hysterectomy, deep endometriosis surgery and sacrocolpopexy, pose risks to autonomic pelvic nerves leading to voiding dysfunction and reduced quality of life. This review article …
Accurate reporting of participants' race and ethnicity is essential for assessing the representativeness of study populations and for identifying potential disparities in diagnosis, treatment, and outcomes.
The female reproductive system (FRS) exhibits unique immunological characteristics, balancing defense against pathogens with tolerance to sperm and semi-allogeneic embryos. Key players include decidual natural killer (dNK) cells, immune checkpoint …